Q.9 Match List-I with List-II
| List-I | List-II |
|---|---|
| (Vitamin precursor) | (Deficiency disease) |
| (A) Vitamin B1 | (I) Pernicious anemia |
| (B) Vitamin B2 | (II) Beriberi |
| (C) Vitamin B6 | (III) Growth retardation |
| (D) Vitamin B12 | (IV) Dermatitis |
Choose the correct answer from the options given below:
- (A) – (I), (B) – (II), (C) – (III), (D) – (IV)
- (A) – (II), (B) – (III), (C) – (IV), (D) – (I)
- (A) – (I), (B) – (II), (C) – (IV), (D) – (III)
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Option 1: (A)–(I), (B)–(II), (C)–(III), (D)–(IV) Incorrect—misassigns Vitamin B1 (beriberi) to pernicious anemia and B2 (not beriberi) to beriberi.
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Option 2: (A)–(II), (B)–(IV), (C)–(III), (D)–(I) Correct—B1 causes beriberi (II); B2 leads to dermatitis (IV); B6 deficiency shows growth retardation (III); B12 results in pernicious anemia (I).
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Option 3: (A)–(I), (B)–(II), (C)–(IV), (D)–(III) Incorrect—wrongly links B1 to pernicious anemia (B12’s disease) and swaps beriberi/dermatitis.
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Option 4: (A)–(III), (B)–(IV), (C)–(I), (D)–(II) Incorrect—confuses B1 (not growth retardation), B6 (not pernicious anemia), and B12 (not beriberi).(A) – (III), (B) – (IV), (C) – (I), (D) – (II)
The correct answer is option 2: (A) – (II), (B) – (IV), (C) – (III), (D) – (I), as it accurately matches each B vitamin precursor with its classic deficiency disease.
Question Breakdown
This matching question from exams like GATE Life Sciences evaluates knowledge of B vitamin deficiencies and their clinical manifestations.
Introduction to Vitamin Deficiency Matching List-I List-II
Vitamin deficiency matching List-I List-II questions link precursors like Vitamin B1, B2, B6, and B12 to diseases such as beriberi and pernicious anemia, key for GATE Life Sciences preparation. These water-soluble vitamins act as coenzymes in metabolism; deficiencies arise from poor diet, malabsorption, or alcoholism.
Vitamin B1 (Thiamine) and Beriberi
Vitamin B1 deficiency causes beriberi (II), with wet (cardiac edema, heart failure) and dry (neuropathy, muscle wasting) forms due to impaired carbohydrate metabolism and nerve function.
Vitamin B2 (Riboflavin) Dermatitis
Vitamin B2 deficiency leads to dermatitis (IV), including angular stomatitis, glossitis, and skin lesions around mouth/nose, plus normocytic anemia from flavin coenzyme disruption in redox reactions.
Vitamin B6 (Pyridoxine) Growth Issues
Vitamin B6 deficiency manifests as growth retardation (III) in children, convulsions, anemia, and dermatitis; it’s vital for amino acid metabolism and neurotransmitter synthesis.
Vitamin B12 (Cobalamin) Pernicious Anemia
Vitamin B12 deficiency causes pernicious anemia (I), with megaloblastic anemia, neuropathy, and glossitis due to intrinsic factor lack impairing absorption and folate metabolism.
Vitamin (List-I) Deficiency Disease (List-II) Key Symptoms At-Risk Groups (A) B1 (Thiamine) (II) Beriberi Neuropathy, edema Alcoholics, rice-based diets (B) B2 (Riboflavin) (IV) Dermatitis Skin lesions, stomatitis Poor nutrition (C) B6 (Pyridoxine) (III) Growth retardation Seizures, anemia Infants, malabsorption (D) B12 (Cobalamin) (I) Pernicious anemia Megaloblastic anemia Vegans, gastric issues -
