110. You have purified a protein X and observed the following A. When run on a native PAGE, it gives rise to a single band. B. When run on a […]
Tag: dbt jrf pyq 2021
Tag: dbt jrf pyq 2021
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Understanding Profile Alignment and Hidden Markov Models: Key Differences
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- April 13, 2025
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109. A profile can be generated from a multiple sequence alignment by obtaining positionspecific preference (or probability) of each amino acid. This can be used to identifyhomologs. However, the key […]
Assessing Structural Similarity of Biomolecules: Key Metrics and Methods
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- April 13, 2025
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108. Which one of the following will be used to assess structural similarity of biomolecules? (a) E-value , (b) P-Value, (c) Root mean square deviation, (d) Standard deviation Assessing Structural […]
Understanding Dihedral Angles in Protein Structure: How Many Atomic Positions Are Needed?
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- April 13, 2025
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107. How many atomic positions are required to measure a dihedral angle? (a) Five (b) Four (c) Three (d) Two Understanding Dihedral Angles in Protein Structure: How Many Atomic Positions […]
Understanding the D-[TS]-x-(2)-{GH}-L Motif in Protein Sequences
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- April 13, 2025
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106. The motif D-[TS]-x-(2)-{GH}-L motif will have sequence: (a) DRRRRL (b) DSARRL (c) DSRRGL (d) DTRRHL Understanding the D-[TS]-x-(2)-{GH}-L Motif in Protein Sequences Protein sequences are made up of various […]
Understanding the K-Tuple Method in Bioinformatics: Its Role in Sequence Similarity
105. K-tuple method is associated with: (a) Dot matrix , (b) Dynamic programming , (c) Multiple sequence alignment, (d) Sequence similarity Introduction In bioinformatics, sequence analysis plays a crucial role […]
Understanding In Vitro ADMET Analysis: What It Can and Cannot Reveal
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- April 13, 2025
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104. The in vitro ADMET analysis cannot provide information about: (a) Cytochrome P450 inhibition, (b) Adverse reaction to the drug , (c) Blood-brain barrier penetrability, (d) Metabolic Stability, Introduction ADMET […]
Choosing the Right Scoring Matrix in BLAST for Sequence Similarity Searches
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- April 13, 2025
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103. A protein sequence was isolated from a novel source. During an initial sequencesimilarity search through BLAST, no homologous sequence was identified. A furtherBLAST search should be run by changing […]
Understanding CASP: How It Evaluates Protein Structure Prediction Techniques
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- April 13, 2025
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102. CASP judges one of the following: (a) Experimental techniques of structure determination, (b) Quality of protein structures, (c) Suitability of drug , (d) Techniques of protein structure prediction Introduction: […]
Understanding Sequence Alignment with Needleman-Wunsch Algorithm: Best Score Calculation
101. Two sequences PLAVAV and PLLV were aligned using Needliman-Wunsch algorithm with the scores, match = 1, mismatch = -1, gap initiation = -1, gap elongation = -2. The alignment […]


