106. The motif D-[TS]-x-(2)-{GH}-L motif will have sequence:
(a) DRRRRL
(b) DSARRL
(c) DSRRGL
(d) DTRRHL

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Understanding the D-[TS]-x-(2)-{GH}-L Motif in Protein Sequences

Protein sequences are made up of various motifs that serve as critical elements in defining the protein’s structure and function. One such motif is the D-[TS]-x-(2)-{GH}-L motif, which appears in numerous proteins involved in specific biological functions.

In this article, we will break down this motif, explain how it works, and discuss which protein sequence best matches it.

What is the D-[TS]-x-(2)-{GH}-L Motif?

A motif is a conserved sequence within a protein that often holds a specific function, such as enzyme catalysis, DNA binding, or interaction with other proteins. The D-[TS]-x-(2)-{GH}-L motif can be understood by breaking it down into smaller components:

• D: This represents the amino acid Aspartic acid (D).

• [TS]: Indicates that the next position can be either Threonine (T) or Serine (S).

• x: Denotes any amino acid.

• (2): Refers to two amino acids between the x and {GH} part of the motif.

• {GH}: A conserved Glycine (G) and Histidine (H) in the sequence.

• L: The last amino acid is Leucine (L).

Together, this motif forms a pattern in protein sequences that could be important for their function.

Which Sequence Matches the D-[TS]-x-(2)-{GH}-L Motif?

From the options provided, the correct sequence that aligns with the D-[TS]-x-(2)-{GH}-L motif is:

(c) DSRRGL

Let’s break it down:

• D is Aspartic acid (matches the D in the motif).

• S is Serine (matches the [TS] in the motif).

• R and R are amino acids between the {GH} part (the x part of the motif can be any amino acid, so this is valid).

• G is Glycine (matches the G in {GH}).

• L is Leucine (matches the L in the motif).

Therefore, the sequence DSRRGL fits the motif D-[TS]-x-(2)-{GH}-L perfectly.

Conclusion

The D-[TS]-x-(2)-{GH}-L motif is an essential part of understanding protein function and structure. By knowing the specific amino acids involved in these motifs, researchers can make predictions about the protein’s role and interactions. For this motif, the sequence DSRRGL is the correct match.