Q.32 Match Group I with Group II

Options:

(A) P-2, Q-1, R-4, S-3

(B) P-3, Q-2, R-1, S-4

(C) P-4, Q-2, R-1, S-3

(D) P-4, Q-1, R-2, S-3

Introduction

“Match the following” questions are common in life-science competitive exams and require strong conceptual clarity. This question tests knowledge of cell adhesion proteins, hormones, protease inhibitors, and iron-transport proteins. Let us analyze each pair carefully to identify the correct answer.

Step-by-Step Matching Explanation

P. Fibronectin → 4. Cell attachment to substratum

Fibronectin is an extracellular matrix (ECM) glycoprotein that mediates cell adhesion by binding to integrins on the cell surface.

✅ Correct match: P-4

Q. Insulin → 1. Uptake of amino acids and glucose

Insulin is a peptide hormone that stimulates:

• Glucose uptake

• Amino acid uptake

• Protein synthesis

✅ Correct match: Q-1

R. α-Macroglobulin → 2. Trypsin inhibitor

α-Macroglobulin is a broad-spectrum protease inhibitor that inhibits enzymes like trypsin and protects tissues from proteolytic damage.

✅ Correct match: R-2

S. Transferrin → 3. Binds iron

Transferrin is a plasma protein responsible for transporting iron (Fe³⁺) in the blood.

✅ Correct match: S-3

Correct Matching Sequence

P-4, Q-1, R-2, S-3

Correct Answer

✅ Option (D)

Explanation of All Options

Option (A): P-2, Q-1, R-4, S-3

❌ Incorrect

• Fibronectin is not a trypsin inhibitor

• α-Macroglobulin does not mediate cell attachment

Option (B): P-3, Q-2, R-1, S-4

❌ Incorrect

• Fibronectin does not bind iron

• Insulin is not a protease inhibitor

• Transferrin does not aid cell attachment

Option (C): P-4, Q-2, R-1, S-3

❌ Incorrect

• Insulin is wrongly matched with trypsin inhibitor

• α-Macroglobulin does not control glucose uptake

Option (D): P-4, Q-1, R-2, S-3

✔ Correct

• All biological functions are accurately matched

Key Takeaways

• Fibronectin → cell adhesion

• Insulin → nutrient uptake

• α-Macroglobulin → protease inhibition

• Transferrin → iron transport

Conclusion

The correct matching of Group I with Group II is P-4, Q-1, R-2, S-3, which corresponds to Option (D). Understanding protein function relationships is essential for scoring well in life-science competitive examinations.