Q.69 Match List–I with List–II :
| List–I (Hormone/Factor) |
List–II (Role) |
|---|---|
| (A) Erythropoietin | (I) Enhancement of immune function |
| (B) Platelet derived growth factor | (II) Treatment of infertility |
| (C) Chorionic gonadotropin | (III) Stimulate formation of RBCs |
| (D) Interleukin | (IV) Stimulate wound healing |
Choose the correct answer from the options given below :
- (A)–(III); (B)–(IV); (C)–(II); (D)–(I)
- (A)–(IV); (B)–(III); (C)–(II); (D)–(I)
- (A)–(IV); (B)–(III); (C)–(I); (D)–(II)
- (A)–(III); (B)–(IV); (C)–(I); (D)–(II)
Erythropoietin, PDGF, chorionic gonadotropin, and interleukins each play distinct roles in hematopoiesis, tissue repair, reproduction, and immunity. The correct matching aligns their primary physiological functions for exam success.
Correct Answer
(A)–(III); (B)–(IV); (C)–(II); (D)–(I) is right.
Erythropoietin (A) – (III)
Erythropoietin (EPO), produced mainly by kidneys, binds receptors on erythroid progenitors to stimulate red blood cell (RBC) formation in bone marrow via JAK-STAT signaling, increasing hemoglobin in response to hypoxia.
PDGF (B) – (IV)
Platelet-derived growth factor (PDGF) recruits fibroblasts, smooth muscle cells, and macrophages to injury sites, promoting chemotaxis, proliferation, and collagen deposition to accelerate wound healing and tissue remodeling.
Chorionic Gonadotropin (C) – (II)
Human chorionic gonadotropin (hCG), secreted by placental trophoblasts, sustains corpus luteum progesterone production early in pregnancy; recombinant hCG treats infertility in ovulation induction protocols.
Interleukin (D) – (I)
Interleukins (e.g., IL-2, IL-12) are cytokines that enhance T-cell proliferation, B-cell differentiation, NK cell cytotoxicity, and antibody production, bolstering adaptive and innate immune responses.
Options Analysis
Option A B C D Status 1st III IV II I ✅ Correct 2nd IV III II I ❌ Swaps A/B 3rd IV III I II ❌ Wrong C/D 4th III IV I II ❌ Wrong C/D
