Category: CSIR NET Life Science Previous Year Questions and Solution CELL SIGNALING

34. The cycling of monomeric G proteins, such as Ras, between active and inactive states is aided by accessory proteins that bind to the G protein and regulate its activity. […]

33. G protein-coupled receptors (GPCRs) are used to detect and respond to many different types of signals, including neurotransmitters, hormones involved in glycogen and fat metabolism and even photons of […]

32. The signal transduction pathway involved in glycogen metabolism triggered in the liver by the hormone epinephrine involves the following steps: (A) Activation of G protein (Gαβγ) by the activated […]

31. Glucose is mobilized in muscle when epinephrine activates Gas. In an experiment in which muscle cells were stimulated with epinephrine, glucose mobilization was observed even after withdrawal of epinephrine. […]

30. In cells having G protein coupled receptor, inhibition of protein kinase A by siRNA technology led to diminished transcription of androgen binding protein (ABP) and CREB protein. Addition of […]

29. G-protein coupled receptors (GPCR) consist of three protein subunits  α, β and γ. In unstimulated state, a- subunit is GDP bound and GPCR is inactive. When GPCR gets activated. […]

28. Which one of the following events NEVER activates the G-protein coupled receptor for sequestering Ca2+ release? (1) Interaction of bind in to sperm receptors. (2) Activation of Frizzled by […]

27. Which one of the following statements about receptor – enzyme isFALSE? (1) A receptor enzyme has an extracellular ligand binding domain, a transmembrane domain and an intracellular catalytic (enzyme) […]

26. The second messenger CAMP, synthesized by adenylyl cyclase transduces a wide variety of physiological signals in various cell types in mammalian cells. Most of the diverse effects of cAMP […]

25. In signal transduction trimeric G protein with α,β and γis involved. Which subunit will activate adenylate cylase (1) α subunit        (2) β subunit (3) γ  subunit       (4) All three […]