Q46.Match List I with List II
List I
A. Bone marrow
B. Spleen
C. Lymph Node
D. Thymus
List II
I. Hematopoiesis
II. T-cell maturation
III. Filtration of blood-borne antigen
IV. Filtration of tissue-associated antigen
Choose the correct answer from the options given below :
(1) A-I, B-IV, C-II, D-III
(2) A-III, B-I, C-II, D-IV
(3) A-II, B-I, C-IV, D-III
(4) A-I, B-III, C-IV, D-II
Bone marrow is the primary site for hematopoiesis, while the thymus handles T-cell maturation, spleen filters blood-borne antigens, and lymph nodes manage tissue-associated antigens. The correct matching is option (4): A-I, B-III, C-IV, D-II.
Correct Matching
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A. Bone marrow → I. Hematopoiesis: Bone marrow produces all blood cells, including lymphocytes, through hematopoiesis.
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B. Spleen → III. Filtration of blood-borne antigen: The spleen filters blood, trapping and removing pathogens and antigens circulating in the bloodstream.
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C. Lymph Node → IV. Filtration of tissue-associated antigen: Lymph nodes filter lymph fluid, capturing antigens from tissues via lymphatic drainage.
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D. Thymus → II. T-cell maturation: The thymus is where T-lymphocytes mature and undergo selection.
Option Analysis
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Option (1) A-I, B-IV, C-II, D-III: Incorrect. Spleen does not filter tissue antigens (IV; lymph nodes do), and thymus does not filter blood antigens (III).
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Option (2) A-III, B-I, C-II, D-IV: Incorrect. Bone marrow is not for blood antigen filtration (III; spleen is), and spleen is not for hematopoiesis (I).
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Option (3) A-II, B-I, C-IV, D-III: Incorrect. Bone marrow does not mature T-cells (II; thymus does), and spleen is not primarily for hematopoiesis postnatally.
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Option (4) A-I, B-III, C-IV, D-II: Correct, as explained above.
Bone marrow, spleen, lymph node, and thymus are key lymphoid organs in the immune system, often tested in NEET Biology’s Human Health and Disease chapter. This bone marrow spleen lymph node thymus matching question (Q46) links List I organs to List II functions like hematopoiesis and antigen filtration. Understanding their roles in hematopoiesis, T-cell maturation, and filtration of blood-borne or tissue-associated antigens is crucial for NEET aspirants preparing for exams.
Functions of Lymphoid Organs
Primary lymphoid organs like bone marrow and thymus handle cell production and maturation, while secondary ones (spleen, lymph nodes) filter antigens.
Why Option (4) is Correct
This matching aligns with NCERT: Bone marrow for hematopoiesis, spleen for blood-borne antigen filtration, lymph nodes for tissue-associated antigen filtration, and thymus for T-cell maturation. Other options mismatch roles, e.g., option (1) wrongly assigns tissue filtration to spleen.


