27. Which one of the following statements about receptor – enzyme isFALSE? (1) A receptor enzyme has an extracellular ligand binding domain, a transmembrane domain and an intracellular catalytic (enzyme) […]
26. The second messenger CAMP, synthesized by adenylyl cyclase transduces a wide variety of physiological signals in various cell types in mammalian cells. Most of the diverse effects of cAMP […]
25. In signal transduction trimeric G protein with α,β and γis involved. Which subunit will activate adenylate cylase (1) α subunit (2) β subunit (3) γ subunit (4) All three […]
24. C-AMP is directly involved in regulation of (1) Adenylate cyclase (2) Protein kinase A (3) Phosphofrucotokinase (4) ATP Cyclic AMP (cAMP) and Its Role in Cellular Regulation Introduction Cyclic […]
23. Vibrio cholrae causes diahorrea by (1) Closing ion channels (2) Constitutive expression of adenylate cyclase (3) Closing absorption of water from gut epithelium (4) Destroys cells of intestinal lining […]
22. The mode of action of cholera toxin in causing diarrhoea is by: (1) inactivating Gi protein. (2) continuousactivation of adenylyl cyclase. (3) locking GS protein in an inactive state. […]
21. In small intestine, cholera toxin acts by (1) active absorption of NaCl (2) activation of GTPase (3) inhibition of adenylyl cyclase (4) ADP-ribosylation of the G-protein Introduction Cholera toxin, […]
In the above signaling cascade, which of the following molecules is denote by ‘B’? (1) single-pass. (2) three-pass (3) five-pass. (4) Seven-pass. Understanding the Structure of Cellular Receptors: Identifying ‘B’ […]
(JUNE 2019) 12- Following are the list of some cellular receptors (Column X) and With possible functional characteristics (Column Y): Column X Column Y A. Asialoglyco protein receptor (i) […]
The table below summarizes the key signaling pathways that orchestrate development, their receptors, transcription effectors and output. SIGNALING PATHWAY RECEPTOR TRANSCRIPTIONAL EFFECTOR OUTPUT A Wnt Thick veins β-catenin Patterning B […]