36. Which one of the following is not a G-protein coupled receptor? (1) Epinephrine receptor (2) Transferrin receptor (3) Glucagon receptor (4) Thyroid stimulating hormone receptor Introduction: G-protein coupled […]
35. Although a majority of G protein-coupled receptors (GPCRs) act through adenylyl cyclase, many of them (GPCR) exert their effects by activating the plasma membrane-bound enzyme phospholipase C-β (PLC-β). These […]
34. The cycling of monomeric G proteins, such as Ras, between active and inactive states is aided by accessory proteins that bind to the G protein and regulate its activity. […]
33. G protein-coupled receptors (GPCRs) are used to detect and respond to many different types of signals, including neurotransmitters, hormones involved in glycogen and fat metabolism and even photons of […]
32. The signal transduction pathway involved in glycogen metabolism triggered in the liver by the hormone epinephrine involves the following steps: (A) Activation of G protein (Gαβγ) by the activated […]
31. Glucose is mobilized in muscle when epinephrine activates Gas. In an experiment in which muscle cells were stimulated with epinephrine, glucose mobilization was observed even after withdrawal of epinephrine. […]
30. In cells having G protein coupled receptor, inhibition of protein kinase A by siRNA technology led to diminished transcription of androgen binding protein (ABP) and CREB protein. Addition of […]
29. G-protein coupled receptors (GPCR) consist of three protein subunits α, β and γ. In unstimulated state, a- subunit is GDP bound and GPCR is inactive. When GPCR gets activated. […]
28. Which one of the following events NEVER activates the G-protein coupled receptor for sequestering Ca2+ release? (1) Interaction of bind in to sperm receptors. (2) Activation of Frizzled by […]
