In a laboratory experiment it was observed that both ‘Virus A’ and ‘Virus B’ could infect a mammalian host cell, when infected individually. Interestingly, if the cell were first infected […]
In an organism, expression of gene ‘X’ is induced in the presence of a hormone genetic analysis showed that the hormonal signal is transduced through two proteins Let1 and Let(2) […]
70. The following patterns of gene expression wereobtained after activating Notch I receptor with twodifferent ligands Dll1, and Dll4 Which one of the following statements depicts the correct of observations? […]
69. The extracellular domain of a cell surface receptor (A) was switched with the extracellular domain of another receptor (B) to create a chimeric receptor (B-A). Assuming that there is […]
64. Binding of a ligand to a cell-surface receptor activates an intracellular signal transduction pathway through the sequential activation of four protein kinases. In the human cell line A, these […]
63. A ligand recognizes two different cell surface receptors. A and B, on the same cell type. Receptor A. after with the ligand internalized along with the ligand whereas receptor […]
62. Cultured animal cells were transfected with expression vector encoding either ß-galactosidase (β-gal) alone or expressing a fusion protein of β-gal and glucocorticoid receptor (GR). After transfection. cells were kept […]
61. A pharmacy student designed a drug to specifically target the receptors for retinoic acid in order to prevent stem cell differentiation. After in vitro trial, the investigator found that […]
60. Based on the structural regions of a nuclear receptorshown in the diagram, the following predictions weremade. A) Region F is responsible for binding to ligands and contains two zinc […]
59. Which one of the following state about the nuclear receptor super family is NOT true? (1) The receptors are always cytosol where they remain associated with heat-shock proteins and […]
