The HIPPO signaling pathway is important for cell proliferation. It is regulated by the protein kinases MST1/2 and LATS1/2 and the transcriptional activators YAP and TAZ. Accordingly, the following events […]
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CSIR NET Life Science Previous Year Questions and Solution on EXTENSION OF MENDELIAN PRINCIPLES (62)
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Morphogen Gradients and Neural Induction in Zebrafish and Comparison to Other Vertebrates
The figure above represents a late zebrafish gastrula. The following concepts may be proposed during further development of the embryo. A. The concentration of FGF decreases from the yolk towards […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Role of the Hippo Signaling Pathway in Mammalian Inner Cell Mass Formation
Hippo pathway is responsible for the trophoblast and inner cell mass (ICM) differentiation during mammalian development. Which one of the following is true for ICM formation? (1) The Tead4 transcription […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
How Sperm Entry and PAR Proteins Establish the Anterior-Posterior Axis in C. elegans
11. Gradients of morphogens determine the future dorsal- ventral and anterior-posterior axes of the developing embryo in many organisms. How is the anterior- posterior axis developed in C. elegans? (1) […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Key Facts About Totipotency and Pluripotency in Mammalian Development
The following statements are made about mammalian development: (A) Zygote is a totipotent stem cell. (B) The cells of inner cell mass are said to be pluripotent. (C) The three […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Matching Fate Maps and Cleavage Patterns: Finding the Right Combination in Embryology
10. Given below are fate map of two organisms and the pattern by which embryos undergo cleavage. Which of the following is/are the right combination(s)? (1) B only […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
The Core Transcription Factors Maintaining Pluripotency in Mammalian Inner Cell Mass
The pluripotency of the inner cell mass in mammals is maintained by a core of three transcription factors namely, (1) Oct 4, Sox 2 and Nanog (2) Oct 4, Sox […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Role of Cdx2 and Oct4 in Early Mammalian Embryonic Cell Fate Decisions
The following demonstrates proposed functions of different genes which determine the decision to become either trophoblast or inner cell mass (ICM) blastomere during early mammalian development: Based on the above […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Stem Cell Niches: Key Regulators of Self-Renewal and Cell Survival
The following are certain statements regarding stem cells: (A) All types of stem cells have the ability to give rise to a complete embryo. (B) Multipotent stem cells are those […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Matching Embryonic Cleavage Patterns with Representative Species: A Comprehensive Guide
The table below lists cleavage pattern and names of species. Match the cleavage patterns with the species. (1) A- i; B- ii; C- iii; D- iv (2) A- ii; B- […]
