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In tadpoles, if the tail is amputated it can regenerate. However, if the tail is amputated and then exposed to retinoic acid, it develops limbs instead of regenerating the tail. […]

Sonic hedgehog (Shh) specifies the anterior-posterior axis during limb development. Which one of the following statements regarding it is correct? (1) Shh secreting cells undergo apoptosis after performing its function. […]

Following figure shows the early interactions between the Apical Ectodermal Ridge (AER) and the limb bud mesenchyme. The red lines with block head indicate repression while the black lines indicate […]

The mechanisms specifying the three axes of a tetrapod limb are interrelated and coordinated. In case of chick limb development the following statements were made: A. In the positive feedback […]

During wing development in chick, if Apical Ectodermal Ridge (AER) is removed, the limb development ceases, on the other hand placing leg mesenchyme directly beneath the wing AER, distal hindlimb […]

In the context of the proximal-distal growth and differentiation of a tetrapod limb following experiments were visualized (A) If the apical ectodermal ridge (AER) is removed at any time during […]

A set of experiments that were carried out to demonstrate the effect of Apical Ectodermal Ridge (AER) of the chick limb bud on the underlying mesenchyme are enlisted below, along […]

The proximal distal growth and differentiation of the tetrapod limb bud are made possible by a series of interactions between the apical ectodermal ridge (AER) and limb bud mesenchyme directly […]

During vertebrate limb development, a specialized ectodermal structure, called Apical Ectodermal Ridge (AER), forms at the dorso-ventral ectodermal boundary at the distal tip of the developing limb bud. The following […]

What would happen as a result of a transplantation experiment in a chick embryo where the leg mesenchyme is placed directly beneath the wing apical ectodermal ridge (AER)? (1) Distal […]