Which one of the following statements is NOT correct regarding the tetrapod limb development? (1) As the limb grows outward, the stylopod forms first, then the zeugopod and the autopod […]
Homeobox transcription factor (Hox proteins), play important roles in specifying whether a particular mesenchymal cell will become stylopod, zeugopod or autopod. Based on the expression patterns of these genes, a […]
When a wrist blastema from a recently cut Axolotl forelimb is placed on a host hindlimb cut at the mid thigh level, it will generate only a wrist. The host […]
The programmed cell death that separates the digits during a tetrapod limb development is dependent on which one of the following signaling pathways? (1) BMP (2) FGF (3) Wnt (4) […]
46. Which one of the following statements regarding limb regeneration in Salamander is correct? (1) A normal limb is regenerated after amputation, irrespective of whether the cut was made below […]
How will the regeneration of a newt limb be affected if the nerve supply is severed before amputation? (1) Partial regeneration will occur where only the proximal structures will be […]
What would be the effect on newt limb regeneration, if more than 90% of the nerve supply is severed before amputation? (1) The apical ectodermal cap stimulates growth of the […]
Which of the following is true about amphibian limb regeneration? (A) It requires a minimum number of functional nerves. (B) The blastema of an amputated limb, if transplanted in the […]
Dose-dependence of retinoic acid treatment supports the notion that a gradient of retinoic acid can act as a morphogen along the proximo-distal axis in a developing limb. Following are certain […]
What would be the effect of retinoic acid (RA) treatment on the ‘positional information’ of blastema cells present on the amputated newt limb? (1) RA will have no effect (2) […]