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26. The following are some statements made regarding mutations: A. Change of DNA sequence from AGC to ATC in non- coding strand can have a major impact on the protein […]

25. A protein has Gly at position 28 (wild type). On mutagenesis, a point mutation leads to conversion of Gly to Arg at position 28 (mutant 1). When mutant 1 […]

24. The base analog 2-aminopurine pairs With thymine, and can occasionally pair with cytosine. The type of mutation induced by 2-aminopurine is (1) transversion       (2) Transition. (3) deletion             (4) nonsense. […]

23. Dearnination of bases is a common chemical event that produces spontaneous mutation. Which one of the following bases will be formed by deamination of 5-methylcytosine? (1) Uracil                (2) Thymine […]

22. 2- Aminopurine induces mutation by (1) Base pair change.   (2) Frameshift (3) Duplication             (4) Deletion 2-Aminopurine (2AP), an adenine base analog, primarily induces mutations through base pair changes, specifically […]

21. Which one of the following chemicals is a DNA intercalator? (1) 5-Bromouracil (2) Ethyl methane sulfonate (3) Acridine orange (4) UV Acridine orange is the correct DNA intercalator among […]

20. 5-Bromouracil is a base analog that can cause mutation when incorporated into DNA. Which of the following is the most likely change that 5-Bromouracil induces: (1) T:A to C:G           […]

19. Which of the following mutagens is most likely to results in a single amino acid change in a gene product? (1) Acridine orange    (2) X-rays (3) EMS                    (4) Ethidium […]

18. Ames test is used to evaluate mutagens in the environment. Which of the following statements, about Ames test are true? A. The mutagenic effect of a compound tested using […]

17. To replace animal use in testing hepatic toxicity of a drug on trial, which one of the following would be used in vitro to be closest to the in […]