16. Which eukaryotic RNA polymerase transcribes t-RNA genes?
(1) RNA polymerase I        (2) RNA polymerase II
(3) RNA polymerase III     (4) DNA polymerase I

Which Eukaryotic RNA Polymerase Transcribes tRNA Genes?

RNA polymerase III is the enzyme responsible for transcribing tRNA genes in eukaryotic cells. This polymerase also synthesizes other small RNAs, such as 5S rRNA and some small nuclear and nucleolar RNAs.

• RNA polymerase I transcribes most rRNA genes (except 5S rRNA).

• RNA polymerase II transcribes mRNA and many small regulatory RNAs.

• DNA polymerase I is not an RNA polymerase; it is involved in DNA replication and repair.

Supporting Evidence

• “RNA polymerase III transcribes the genes for tRNAs and for the smallest species of ribosomal RNA (5S rRNA).

• “RNA polymerase (pol) III transcribes a multitude of tRNA and 5S rRNA genes as well as other small RNA genes distributed through the genome”.

• “RNA polymerase III (Pol III) transcribes a limited set of short genes in eukaryotes producing abundant small RNAs, mostly tRNA”.

• “In eukaryote cells, RNA polymerase III (also called Pol III) is a protein that transcribes DNA to synthesize 5S ribosomal RNA, tRNA, and other small RNAs”.

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