The genetic code has 61 codons for amino acids and termination codons. How protein synthesis is terminated? (1) There are specific tRNAs for stop codons (2) Release factors mediate termination […]
Tag: post translational modification pyq
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CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Ribosomal Translocation in E. coli: Mechanism, GTP/EF-G Dependence, and In Vitro vs. In Vivo Dynamics
During elongation step or protein synthesis, translocation moves the mRNA and the peptidyl t-RNA by one codon through the ribosome. Translocation in E.coli involves GTP and EF-G. However, in vitro […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Protein Synthesis and Trypsin Digestion: Which Peptide Fragment Carries Maximum 14C Label at Early Synthesis Stage?
A protein has 4 equally spaced trypsin sensitive sites which results in peptide fragments A1, A2, A3, A4 and A5 upon digestion with trypsin. Peptides A2 and As, represents N-terminal […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Ribosome Recycling in Bacteria: The Essential Roles of RRF and EF-G
For continuation of protein synthesis in bacteria, ribosome need to be released from the mRNA as well as to dissociate into subunits. These processes do not occur spontaneously. They need […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Translation Initiation Factor IF3: The Anti-Association Factor for 30S and 50S Ribosomal
Which one of the following translation factors is used at the step Of translation initiation and defined as anti- association factor for 30S and 50S subunit interactions? (1) IF1 (2) […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
How Internal Ribosomal Entry Sites Promote Translation Under Stress
Presence of an internal ribosomal entry site (IRES) in mRNA (1) Inhibit its translation (2) promotes its post transcriptional processing (3) has no impact on its translation (4) promotes its […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Why the First AUG Isn’t Always the Start in Eukaryotic mRNAs
It has been observed that in 5-10% of the eukaryotic mRNAs with multiple AUGs, the first AUG is not the initiation site, In such cases, the ribosome skips over one […]
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Circular mRNA and Protein Synthesis: Mechanisms Behind Rapid Translation in Eukaryotic Cells
presence of Circular mRNAs a specific protein in an eukaryotic cell reflects a rapid rate of synthesis Of that protein. following mechanisms are suggested: A) Eif-4G and PABP promote this […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
During Translation Termination the Release Factor Binds to Stop Codon
During translation when release factor binds to stop codon on m-RNA in A-site of ribosome, the synthesized translation peptide transferred to (1) t-RNA (2) Water (3) H+(4) Amino acids Introduction […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
The Critical Step During Elongation of Translation is Translocation of the Ribosome
The most critial step during elongation for correct proteins synthesis is (1) Binding of ribosome to m.RNA (2) Formation Initiation complex (3) Aminoacylation of t-RNA (4) Translocation Of ribosome Introduction […]
