41. Which one of the following is the most appropriate statement regarding folded proteins? (1) Charged amino acid side chains are always buried. (2) Charged amino acid side chains are […]
Tag: csir previous year question
Tag: csir previous year question
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Protein Folding: Favorable and Unfavorable Interactions
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- March 25, 2025
- 45 Comments
Which one of the following is unfavorable for protein folding? (1) Hydrophobic interaction (2) van der Waals interaction (3) Conformational entropy (4) Hydrogen bonding Factors Affecting Protein Folding: Favorable and […]
Structural and Functional Analysis of a 30-Residue Polypeptide
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- March 25, 2025
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The following observations are made on a 30-residue polypeptide (a) Unordered structure is observed in water but a helical conformation is observed in medium of low dielectric constant. (b)The peptide […]
Understanding Protein Conformation: Circular Dichroism, Ramachandran Map, and β-Turns
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- March 25, 2025
- 38 Comments
Following are statements related to peptide/protein conformation. A. The circular dichroism spectra of collagen and a protein in α-helical conformation will be identical. B. The allowed region for the dihedral […]
Structure and Characteristics of Globular Proteins
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- March 25, 2025
- 38 Comments
Which statement is correct for globular proteins? (1) Always contain only α helix (2) Always contain only β sheets (3) Contains more reverse turns (4) Contains α helix, β sheets […]
Understanding Protein Folding, van der Waals Interactions,
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- March 25, 2025
- 25 Comments
Out of the statements mentioned below A. L-threonine and L-allo-threonine interact identically with plane polarized light. B. van der Waals’ interactions are always attractive. C. Poly (pro) ll-helix is not […]
The β-α-β Motif: Structure, Function, and Role in Ligand Binding
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- March 25, 2025
- 32 Comments
35. β-α-β motif is composed of two beta strands joined by an alpha helix through connecting loops. This motif is known for (1) ligand binding (2) stereological hindrance in binding […]
Hydrogen Bonding in Alpha-Helices, Beta-Turns, and Beta-Sheets
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- March 25, 2025
- 21 Comments
Following statements are made related to protein structure A. The hydrogen bonding patterns between the CO and NH groups are n → n +3 in α-helix; n → n + […]
Structural Analysis of Adenylate Kinase
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- March 25, 2025
- 25 Comments
Phosphorylation of ADP to ATP occurs through energy metabolism, comprising oxidative phosphorylation or substrate level phosphorylation or photo- phosphorylation (in plants). ATP can also be formed from ADP through the […]
Impact of Alanine-to-Glycine Substitution on Protein Structure
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- March 25, 2025
- 35 Comments
A protein has 30% alanine. If all the alanines are replaced by glycines, (1) helical content will increase. (2) ß-sheet content will increase. (3) there will be no change in […]


