The HIPPO signaling pathway is important for cell proliferation. It is regulated by the protein kinases MST1/2 and LATS1/2 and the transcriptional activators YAP and TAZ. Accordingly, the following events […]
Tag: CSIR NET Life Science PYQs and Solutions Basic Concepts of Development
Tag: CSIR NET Life Science PYQs and Solutions Basic Concepts of Development
CSIR NET Life Science PYQs and Solutions Basic Concepts of Development
No posts found.
Role of the Hippo Signaling Pathway in Mammalian Inner Cell Mass Formation
- admin
- November 8, 2025
- 2 Comments
Hippo pathway is responsible for the trophoblast and inner cell mass (ICM) differentiation during mammalian development. Which one of the following is true for ICM formation? (1) The Tead4 transcription […]
Key Facts About Totipotency and Pluripotency in Mammalian Development
The following statements are made about mammalian development: (A) Zygote is a totipotent stem cell. (B) The cells of inner cell mass are said to be pluripotent. (C) The three […]
The Core Transcription Factors Maintaining Pluripotency in Mammalian Inner Cell Mass
- admin
- November 8, 2025
- 2 Comments
The pluripotency of the inner cell mass in mammals is maintained by a core of three transcription factors namely, (1) Oct 4, Sox 2 and Nanog (2) Oct 4, Sox […]
Role of Cdx2 and Oct4 in Early Mammalian Embryonic Cell Fate Decisions
- admin
- November 8, 2025
- 2 Comments
The following demonstrates proposed functions of different genes which determine the decision to become either trophoblast or inner cell mass (ICM) blastomere during early mammalian development: Based on the above […]
Stem Cell Niches: Key Regulators of Self-Renewal and Cell Survival
- admin
- November 8, 2025
- 2 Comments
The following are certain statements regarding stem cells: (A) All types of stem cells have the ability to give rise to a complete embryo. (B) Multipotent stem cells are those […]
Sequential Role of Key Molecules in Mammalian Embryo Cell Fate Decisions
- admin
- November 8, 2025
- 2 Comments
The decision to become either a trophoblast or inner cell mass blastomere is one of the first decisions taken by any mammalian embryo. Below is a diagrammatic representation of the […]
Key Transcription Factors Governing Mammalian Embryonic Development
- admin
- November 8, 2025
- 2 Comments
Following statement were given regarding decisions taken during development of mammalian embryos (A) Pluripotency of inner cell mass is maintain by a core of three transcription factors, Oct 4, Sox […]
Origin of Embryonic Stem Cells in Mammals: The Inner Cell Mass
- admin
- November 8, 2025
- 3 Comments
The embryonic stem cells in mammals are derived from: (1) Blastocoel (2) Inner cell mass (3) Trophoectoderm (4) Trophoendoderm Embryonic stem cells (ESCs) are foundational to mammalian development and regenerative […]
Potency of Inner Cell Mass Cells in Mammalian Blastocyst: Pluripotency Explained
- admin
- November 8, 2025
- 2 Comments
40. The cells of inner cell mass of a blastocyst stage mammalian embryo are (1) totipotent (2) pluripotent (3) multipotent (4) unipotent In mammalian embryogenesis, the blastocyst stage is a […]


