Given below are a few terms in column A and column B. Which one of the following options represents all correct matches between terms of Column A and Column B? […]
Tag: CSIR NET Life Science Previous Year Questions on applied biology
Tag: CSIR NET Life Science Previous Year Questions on applied biology
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Designing CRISPR/Cas9 editing to remove a faulty exon in DMD
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- November 29, 2025
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Duchenne muscular dystrophy (DMD) is caused by a defective dystrophin gene and can be cured by removing a specific faulty exon. If a CRISPR/Cas9 based genome editing approach is to […]
Role of HIV Vif in preventing APOBEC3G-mediated hypermutation
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- November 29, 2025
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Vif gene is one of the important regulatory gene in lifecycle of HIV virus. It was observed that HIV virus with mutated Vif gene fails to culture of normal T- […]
Factor IX gene delivery – comparing AV, RV and AAV expression profiles
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- November 29, 2025
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Factor IX is essential for blood clotting. Deficiency of Factor IX could be corrected by delivering factor IX gene using viral vectors. In an experiment the gene for Factor IX […]
Choosing the right promoter for macrophage‑specific transgene expression
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- November 29, 2025
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One aims to find out the role of a gene product in macrophages by using a transgenic mouse expressing the genes under a promoter. Which of the following is the […]
Stem cell–based strategies to regenerate functional bone across large defects
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- November 29, 2025
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Stem cell therapies are being used in regenerative medicine like forming new adult bone, which usually does not regrow to bridge wide gaps. Successful attempts have now been made in […]
Identifying the false statement about modern gene therapy
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- November 29, 2025
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Gene therapy is a promising tool for addressing several diseases in humans. With respect to the above, which one of the following statements is FALSE? (1) Gene therapy involves the […]
Which human stem cells are actually used in somatic cell gene therapy?
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- November 29, 2025
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Following are the different ways of obtaining human stem cells- (A) Cells from morula are dispersed and cultured to give rise pluripotent stem cells. (B) Isolated inner cell mass of […]
Safest stem‑cell strategy for liver regeneration using patient‑specific iPS cells
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- November 29, 2025
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Stem cells are widely used for their regenerative property and capacity to differentiate into different lineages. A person with a damaged liver approaches a stem cell therapist. Which of the […]
Explaining transient increase and recovery of muscle tone after caudate lesion
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- November 29, 2025
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The muscle tone was increased after electrolytic lesion of the caudate nucleus in a cat. The muscle tone decreased within seven days. The following explanations were given by the researcher. […]


