27. In eukaryotic chromatin, 30 nm fiber (solenoid) can open up to give rise to two kinds of chromatin. In one type (A), the promoter of a gene within the […]
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CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
5-Azacytidine Reactivates Gene Expression by Inhibiting DNA Methylation: Mechanism and Therapeutic Implications
26. DNA methylation plays an important role in transcription regulation in vertebrates. There is an inverse correlation between the level of DNA methylation in the vicinity of a gene and […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
How Bacteriophage T4 Controls Viral Gene Expression Through Host RNA Polymerase Modification
3. Bacteriophage T4 infects E. coli and injects its DNA inside the cell. The transcription of viral genes occurs in three stages: immediate early, early and late. All the promoters […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Understanding the Peak Expression Phase of DNA Polymerase in Bacteriophage T4 Infection
2. During which phase of infection cycle, the DNA polymerase ofT4 —Phage is expressed maximally (1) Immediate early (2) Early (3) Late (4) Middle Bacteriophage T4 is a well-studied virus […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
How T3 Bacteriophage Regulates Viral Gene Expression: RNA Polymerase Modification Explained
1. Viral gene expression after T3 bacteriophage infection is controlled by: (1) Repressor molecule. (2) Modification of RNA polymerase (3) Slow injection of nucleic acid. (4) DNA polymerase. Bacteriophage T3 […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
How Histone Modifications Affect Chromatin Stability Through Electrostatic Interactions with DNA
25. Phosphorylation of serines as well as methylation and acetylation of lysines in histone tails affect the stability of chromatin structure above the nucleosome level and have important consequences for […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Histone Acetyltransferase Activity of Co-activators Drives Recruitment of Chromatin Remodeling Complexes
24. After activation of a promoter by the DNA binding activity of a transcription factor, a co-activator is recruited at the region targeted for transcription which in turn creates a […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
How Gene Activator Proteins Recruit Histone Acetyltransferases and Chromatin Remodeling Complexes
23. Histone acetylase and chromatin remodeling complexes are recruited to specific regions of chromatin by (1) gene activator proteins. (2) specific promoter sequence (3) phosphorylation of histone acetylase. (4) dephosphorylation […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
NAD-Dependent Histone Deacetylases: Linking Metabolism to Epigenetic Regulation
22. Among the following which enzyme used NAD as cofactor? (1) Histone acetyl transferase (2) Histone methyl transferase (3) Histone deacetylase (4) Histone demethylase Introduction Histone modifications are critical […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Lysine Residues Are the Targets of Histone Deacetylases in Chromatin Regulation
21. Histone deacetylase (HDAC) catalyses the removal of acetyl group from N-terminal of histones. Which amino acid of histone is involved in this process? (1) Lysine (2) Arginine (3) Asparagine […]
