81. A bacterial population has a plasmid with copy number ‘n’. It was observed that on an average in one out of 2(n-1) cell divisions. there was spontaneous plasmid curing. […]
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CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
How RNase H Influences the Mobility of Newly Synthesized DNA Fragments in Urea-PAGE Analysis
In an in vitro experiment using radio-labeled nucleotides, a researcher is trying to analyze the possible products or DNA replication by resolving the products using urea-polyacrylamide gel electrophoresis. In one […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Understanding DNA Supercoiling Removal During Replication: Roles of Helicase and Topoisomerases
Following statements have been made about removal of supercoiling produced by DNA unwinding at the replication fork: Accumulation of supercoils is the result of DNA helicase activity during unwinding of […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Topoisomerases as Targets for Anticancer Drugs: Clarifying Common Misconceptions
As topoisomerases play an important role during replication, a large number of anticancer drugs have been developed that inhibit the activity of these enzymes. Which of the following statements is […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Actinomycin D: DNA Intercalating Antibiotic Blocking RNA Polymerase and DNA Replication in Prokaryotes and Eukaryotes
A polypeptide antibiotic isolated from the genus Streptomyces which intercalates into DNA, preventing the progression of RNA polymerase(s) and initiation of DNA replication both prokaryotes and eukaryotes is (1) Rifampicin […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Ciprofloxacin Mechanism of Action: Inhibition of Bacterial DNA Replication Enzymes
Ciprofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class. The target of antibiotic ciprofloxacin is (1) Replication (2) Protein synthesis (3) Cell wall synthesis (4) Membrane structure […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
How Incorporating Telomere Sequences Restores Stability of Linear Plasmids in Yeast
When circular plasmids having a centromere sequence are transformed into yeast cells, they replicate and segregate in each cell division. However, if a linear chromosome is generated by cutting the […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Telomeres: Protecting Chromosome Ends and Maintaining Genome Integrity
The following statements are made about telomeres: A. proteins (TBPs) are believed to shield telomeres from the cell’s DNA repair machinery, preventing them from being recognized as double-strand breaks, B. […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Which Statement Does NOT Characterize Aging? Insights into Insulin/IGF-1 Signaling, Telomeres, and Lifespan
Which one of the following does NOT characterize aging? (I) An insulin/IGF-I signaling system plays an important role in controlling lifespan. (2) Lifespan increases due to resistance to oxidative stress. […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Telomerase Activity: Key to Telomere Elongation, Aging, and Cancer Immortality
Which statement is correct in relation of activity of telomerase? (1) Increase with age (2) Observed in all cancers and responsible for immortality (3) Responsible for apoptosis but not for […]
