37. Following statements are made about chromatin re-modelling in human cells: A. Local chromatin conformation may play more important role than the local DNA sequence of the promoter. B. Histones […]
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CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Transcriptional Repression Mark is Methylation of Histone H3K9
36. The amino acid side chains of the four histones in the nucleosome are subjected to remarkable variety of post-translation modifications such as phosphorylation, acetylation and methylation. Which one of […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
How Chromatin Remodeling Regulates Transcription in Eukaryotic Genes
35. Chromatin re-modelling leading to histone modifications is invariably required for regulation of transcriptional activity of eukaryotic genes. The residues in histone tails may be methylated or acetylated, The nature […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Topologically Associating Domains and Insulators in Genome Organization and Gene Regulation
34. Following statements were made about some of the characteristics of the human genome: (A) Evidence derived by chromosome conformation capture (3C) suggests that each chromosome comprised a series of […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Biological Significance of Chromatin Remodeling in Eukaryotes
33. Following statements were made about chromatin remodeling in eukaryotes: (A) Chromatin remodeling completely alters and/or slides the nucleosome, but cannot displace it. (B) Chromatin remodeling is an energy driven, […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Tudor Domain Proteins: Readers of Histone Modifications in Chromatin Regulation
32. Readers of histone modifications include: (1) SUN domain proteins (2) BAG domain proteins (3) PAS domain proteins (4) TUDOR domain proteins Introduction Histone modifications are fundamental to the […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
HP1 Function in Mammalian Heterochromatin Formation
31. The mammalian protein HP1 plays a major role in heterochromatinization and silencing. The following mutations are proposed to negatively impact HP1 function. A. Mutation inactivating the deacetylase that targets […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Mutations Relieving Centromeric Silencing in Schizosaccharomyces pombe: Roles of Clr3, Clr4, and Dicer
30. Genes translocated to the heterochromatic regions of chromosomes are silenced. In S. pombe, a translocation event was detected wherein a gene of interest was translocated to the centromere region […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Histone Deacetylase Mutation Relieves Position Effect Variegation in Fission Yeast
29. A gene producing red pigment was placed near centromeres of fission yeast and thus subjected to position effect variegation and produced white colonies, A screen for mutants that increased […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
MicroRNAs: Small Hairpin RNAs Processed into Gene-Regulating Duplexes
Small RNAs with internally complementary sequences that form hairpin-like structure, synthesized as precursor RNAs and cleaved by endonucleases to form short duplexes are called (1) snRNA(2) mRNA (3) tRNA. (4) […]
