All of the following statements about bacterial transcription termination are true EXCEPT
(1) some terminator sequences require Rho protein for termination.
(2) inverted repeat and ‘T’ rich non-template strand define intrinsic terminators.
(3) Rho-dependent terminators may possess inverted repeat elements. Rho
(4) Nus A is necessary for intrinsic transcription termination.
Correct Answer: (4) NusA is necessary for intrinsic transcription termination.
This statement is NOT true, making it the correct answer to the “EXCEPT” question.
Explanation: Bacterial Transcription Termination
In bacteria, transcription termination occurs via two major mechanisms:
1. Intrinsic (Rho-independent) termination
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Requires:
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GC-rich inverted repeat (forms RNA hairpin)
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Followed by a run of uracils (U’s) transcribed from T-rich non-template DNA
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Does not require Rho protein.
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Does not necessarily require NusA, although NusA can enhance hairpin stability and pausing.
2. Rho-dependent termination
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Requires:
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Rho protein
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C-rich, G-poor rut site on RNA
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No strong secondary structure like hairpins
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Statement-wise Analysis:
(1) Some terminator sequences require Rho protein for termination.
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True
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These are Rho-dependent terminators.
(2) Inverted repeat and ‘T’ rich non-template strand define intrinsic terminators.
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True
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These sequences form the RNA hairpin + U-run needed for intrinsic termination.
(3) Rho-dependent terminators may possess inverted repeat elements.
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True
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While not typical or required, some Rho-dependent sites may coincidentally have inverted repeats.
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However, Rho doesn’t rely on hairpin structures for function.
(4) NusA is necessary for intrinsic transcription termination.
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False
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NusA is not essential, though it can enhance intrinsic termination by:
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Stabilizing the hairpin loop
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Increasing pausing of RNA polymerase
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But intrinsic termination can occur without NusA.
60 Comments
Rani Sharma
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Deekshita
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Manisha
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Krishana kumawat
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May 28, 2025Done sir
Arushi
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Ujjwal
May 28, 2025Done
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May 28, 2025Done 👍
Beena Meena
May 28, 2025Done 👍
Shalu Choudhary
May 28, 2025👍👍
Seeta choudhary
May 29, 2025Outstanding explanation 🤞
Renu Saini
May 29, 2025Superb explanation
Vishakha pareek
May 29, 2025Done sir 👍
Mansi Sharma
May 29, 2025Best explanation
Monu
May 29, 2025👍👍👍
Bhanwar Jaat
May 29, 2025👍
Ankita Verma
May 29, 2025👍
Sweta Gupta
May 29, 2025Done ✅
Priyam choudhary
May 29, 2025Done sir 👍
Kabeer
May 29, 2025Done sir ji👍
Komal Pareek
May 30, 2025Clear and concise explanation
Lokesh Kumawat
May 30, 2025Done
Vaishanvi
May 31, 2025Easy , done
Prami Masih
June 1, 2025Done sir ji 👍
Shreeji Charan
June 1, 2025👍
Kabeer narwal
June 3, 2025Done 👍👍
Rohit
June 6, 2025👍🏻👍🏻
Vaidehi Sharma
June 6, 2025Understood👍
Kirti Agarwal
October 26, 2025Statement 4 is incorrect
Santosh Saini
October 26, 20254th statement is not true, making it the correct answer to the except question because intrinsic termination can occur without nus-A
Bhawna Choudhary
October 29, 2025Option 4 is wrong
Sonal Nagar
November 2, 2025Option 4
Roopal Sharma
November 3, 2025Intrinsic termination does not require nus A . Option 4 is incorrect
Anurag Giri
November 3, 2025option 4 is incorrect Intrinsic termination does not require nus A
Heena Mahlawat
November 3, 2025Option 4
Pooja
November 3, 2025NusA is necessary for intrinsic transcription termination
Divya rani
November 3, 20254Th is wrong because NusA protein can enhance intrinsic termination in bacteria but intrinsic termination can occur without NusA.
anjani sharma
November 3, 2025Answer 4 is incorrect
Intrinsic termination does not require nus A .
Aartii sharma
November 3, 2025Option 4 is correct
Mohd juber Ali
November 3, 2025NusA is not necessary for intrinsic transcription termination.however it inhance intrinsic termination by Stabilizing the hairpin loop
HIMANI FAUJDAR
November 3, 2025Ans option 4 is correct because nusA protein is not necessary for termination , though it can enhance intrinsic termination by stabilizing the hairpin loop and increasing pausing of RNA polymerase.
Priya dhakad
November 3, 2025NusA is not necessary for intrinsic transcription termination. So option 4 is correct
Dharmpal Swami
November 3, 2025Intrinsic termination does not require nus A
Dipti Sharma
November 3, 2025NusA is not necessary for intrinsic transcription termination as run of uracil and G-C inverted repeats are necessary for rho independent termination.
Shivani
November 3, 2025Intrinsic termination does not Require Nus-a is not essential, though it can enhance intrinsic termination by nus A .
Sneha kumawat
November 3, 2025Intrinsic termination does not require nus a is not essential , it can enhance intrinsic termination
Anjali sharma
November 3, 2025Statement 4 is incorrect
Kajal
November 4, 2025Correct Answer is: (4) NusA is necessary for intrinsic transcription termination.
Rishita
November 4, 2025NusA is necessary for intrinsic transcription termination. Iss incorrect statement
Rishita
November 4, 2025Ans 4 is incorrect statement
Deepika Sheoran
November 4, 2025Intrinsic termination does not require nus A.
MOHIT AKHAND
November 5, 2025Done sir ✅
sakshi vijay
November 6, 2025option 4 is incorrect
nus A is necessary for intrinsic transcription termination.