Q.27 A protein involved in the formation of intermediate filaments of cytoskeletal framework Lamins G-Actins F-Actins α-tubulins

Q.27 A protein involved in the formation of intermediate filaments of cytoskeletal framework

  1. Lamins
  2. G-Actins
  3. F-Actins
  4. α-tubulins

    Lamins form the nuclear lamina, a type of intermediate filament in the cytoskeletal framework underlying the inner nuclear membrane.

    Option Breakdown

    Lamins

    Lamins (A, B, C types) assemble into intermediate filaments forming the nuclear lamina, providing structural support to the nucleus and anchoring chromatin.

    G-Actins

    G-actins are globular monomers that polymerize into F-actin microfilaments (5-7 nm diameter), not intermediate filaments (10 nm).​

    F-Actins

    F-actins represent filamentous actin, the primary component of thin microfilaments involved in cell motility and contraction.​

    α-Tubulins

    α-tubulins dimerize with β-tubulins to form microtubules (25 nm diameter), part of the spindle apparatus and intracellular transport.​

    Introduction

    Lamins are the protein involved in the formation of intermediate filaments of cytoskeletal framework, unlike G-Actins, F-Actins, and α-tubulins.​

    Cytoskeleton Components

    The cytoskeleton comprises microfilaments (actin), microtubules (tubulin), and intermediate filaments (lamins in nucleus, keratins/vimentin in cytoplasm).

    Protein Comparison Table

    Protein Filament Type Diameter Cellular Role
    Lamins Intermediate 10 nm Nuclear lamina support​
    G-Actins Microfilament monomer 5-7 nm Actin polymerization​
    F-Actins Microfilament 7 nm Cell motility, cytokinesis​
    α-Tubulins Microtubule 25 nm Mitotic spindle, transport​
1 Comment
  • Ankita Pareek
    May 11, 2026

    Lamins involved in the formation of intermediate filaments

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