Q.27 Given below are two statements: Statement I: Rauwolfia serpentina was used by native Indians for snake-bite and as tranquilizer for the treatment of mental disorders. Statement II: Taxol is a drug obtained from plant Taxus brevifolia which is used for treatment of leprosy. In the light of the above statements, choose the most appropriate answer from the options given below: (1) Both Statement I and Statement II are correct (2) Both Statement I and Statement II are incorrect (3) Statement I is correct but Statement II is incorrect (4) Statement I is incorrect but Statement II is correct

Q.27 Given below are two statements:

Statement I:
Rauwolfia serpentina was used by native Indians for snake-bite and as tranquilizer for the treatment of mental disorders.
Statement II:
Taxol is a drug obtained from plant Taxus brevifolia which is used for treatment of leprosy.
In the light of the above statements, choose the most appropriate answer from the options given below:
(1) Both Statement I and Statement II are correct
(2) Both Statement I and Statement II are incorrect
(3) Statement I is correct but Statement II is incorrect
(4) Statement I is incorrect but Statement II is correct

Answer: (3) Statement I is correct but Statement II is incorrect.

Rauwolfia serpentina (sarpagandha) was traditionally used by native Indians for snake bites and as a tranquilizer for mental disorders, while Taxol from Taxus brevifolia treats cancers like ovarian and breast, not leprosy.

Statement Analysis

Statement I – Correct

Rauwolfia serpentina roots, used since 1000 BCE in Ayurvedic texts, treat snake/insect bites, insanity, hypertension, and dysentery via alkaloids like reserpine, which calm nerves and lower blood pressure.

Statement II – Incorrect

Taxol (paclitaxel), isolated from Pacific yew (Taxus brevifolia) bark, stabilizes microtubules to inhibit cancer cell division; it revolutionized chemotherapy for breast, ovarian, and lung cancers since 1992 FDA approval, unrelated to leprosy (caused by Mycobacterium leprae).

Option Explanations

  • (1) Wrong: Statement II false.

  • (2) Wrong: Statement I true.

  • (3) Correct: I true, II false.

  • (4) Wrong: I true.

Rauwolfia serpentina Taxol Taxus brevifolia statement analysis clarifies Statement I correct (snake bite, mental disorders) while debunking Statement II (Taxol not for leprosy, but cancer).

Traditional vs Modern Uses

India’s biodiversity yields Rauwolfia serpentina for tranquilizing via reserpine (50+ alkaloids), sustainable now via tissue culture amid overharvesting. Taxol, from endangered Taxus brevifolia, shifted to semi-synthesis; annual demand exceeds 500 kg for oncology, not bacterial infections like leprosy.

Plant/Drug Source Correct Use Incorrect Claim
Rauwolfia serpentina Roots Snake bite, tranquilizer 
Taxol (paclitaxel) Taxus brevifolia bark Cancer treatment Leprosy 

Exam Insights

Crucial for NEET Botany/GATE Life Sciences: Memorize Rauwolfia (Ayurveda, reserpine) vs Taxol (anticancer); aids bioprospecting in Rajasthan’s herbal zones.

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