Q.44 Match List I with List II
| LIST I Virus |
LIST II Disease |
|---|---|
| A. H1N1 Virus | I. Guillain Barre Syndrome |
| B. Flavi virus | II. Severe Acute Respiratory Syndrome |
| C. Corona Virus | III. Yellow Fever |
| D. Zika Virus | IV. Swine Flu |
Choose the correct answer from the options given below:
1. A-II, B-I, C-III, D-IV
2. A-II, B-I, C-IV, D-III
3. A-IV, B-III, C-II, D-I
4. A-III, B-IV, C-II, D-I
H1N1 causes swine flu, flavivirus yellow fever, coronavirus SARS, and Zika links to Guillain-Barré syndrome.
The correct matching is A-IV (swine flu), B-III (yellow fever), C-II (SARS), D-I (GBS), option 3.
Question Breakdown
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A. H1N1 Virus: 2009 swine flu pandemic
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B. Flavi virus: Flaviviridae family; yellow fever classic example
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C. Corona Virus: SARS-CoV (2003) = Severe Acute Respiratory Syndrome
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D. Zika Virus: Flavivirus; strongly associated with GBS outbreaks (e.g., French Polynesia, Brazil)
Note: “Flavi virus” refers to flaviviruses (Zika/Dengue/YFV); yellow fever fits perfectly.
Option Analysis
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1. A-II, B-I, C-III, D-IV: Wrong (H1N1 ≠ SARS)
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2. A-II, B-I, C-IV, D-III: Wrong (H1N1 ≠ SARS, Corona ≠ swine flu)
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3. A-IV, B-III, C-II, D-I: Correct (all match primary associations)
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4. A-III, B-IV, C-II, D-I: Wrong (H1N1 ≠ yellow fever)
Correct Answer
3. A-IV, B-III, C-II, D-I
Virus-Disease Associations
Key emerging viruses: H1N1 Virus sparked 2009 swine flu pandemic (respiratory). Flavi virus (flaviviruses) cause yellow fever (hemorrhagic liver failure). Corona Virus (SARS-CoV) triggered 2003 Severe Acute Respiratory Syndrome. Zika Virus epidemics linked to Guillain Barre Syndrome (autoimmune neuropathy).
Correct Matching Table
| Virus (List I) | Disease (List II) |
|---|---|
| A. H1N1 | IV. Swine Flu |
| B. Flavi virus | III. Yellow Fever |
| C. Corona Virus | II. Severe Acute Respiratory Syndrome |
| D. Zika Virus | I. Guillain Barre Syndrome |
Why Zika-GBS?
Post-Zika GBS odds ratio >30x; French Polynesia 20/98 GBS cases Zika-confirmed. H1N1 vaccine rarely (~1/million) linked to GBS, but virus itself respiratory.
Exam Strategy
NEET/GATE: H1N1=swine flu (2009), SARS=coronavirus (2003), Zika=GBS/microcephaly (2016), yellow fever=vaccine classic flavivirus. Option 3 perfect—no distractors like COVID (SARS-CoV-2, post-2019).
Vital virology matching for your microbiology prep.
