Q.97 Match the following terms in Column I with the appropriate explanation in Column II
Column I Column II
a) Spliceosome 1) Cell scavengers
b) Peroxisome 2) Metabolism of long chain fatty acids
c) Lysosome 3) Microtubules
d) Centrosome 4) Post transcriptional modifications
(A) a-3; b-1; c-4; d-2 (B) a-4; b-2; c-1; d-3
(C) a-3; b-2; c-1; d-4 (D) a-4; b-3; c-1; d-2
The correct answer is (B) a-4; b-2; c-1; d-3.
Column Matches
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Spliceosome (a) pairs with post-transcriptional modifications (4). This complex removes introns from pre-mRNA during splicing, a key RNA processing step.
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Peroxisome (b) pairs with metabolism of long chain fatty acids (2). It performs beta-oxidation of very long-chain fatty acids and detoxifies hydrogen peroxide.
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Lysosome (c) pairs with cell scavengers (1). These organelles digest waste, pathogens, and damaged components using hydrolytic enzymes.
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Centrosome (d) pairs with microtubules (3). It acts as the main microtubule-organizing center for mitosis and cell structure.
Option Analysis
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(A) a-3; b-1; c-4; d-2: Incorrect. Spliceosome does not organize microtubules; peroxisomes are not primary scavengers.
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(B) a-4; b-2; c-1; d-3: Correct, as detailed above.
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(C) a-3; b-2; c-1; d-4: Incorrect. Spliceosome handles splicing, not microtubules; centrosome does not modify RNA.
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(D) a-4; b-3; c-1; d-2: Incorrect. Peroxisomes manage fatty acid metabolism, not microtubules.
In CSIR NET Life Sciences preparation, mastering spliceosome peroxisome lysosome centrosome functions matching is essential for cell biology questions like . This matching tests knowledge of organelle roles: spliceosome in RNA splicing, peroxisome in fatty acid oxidation, lysosome as cell scavengers, and centrosome in microtubule organization.
Core Functions Explained
The spliceosome catalyzes pre-mRNA splicing by removing introns, enabling post-transcriptional modifications for mature mRNA. Peroxisomes handle metabolism of long chain fatty acids via beta-oxidation and break down peroxides. Lysosomes act as cell scavengers, digesting macromolecules and debris with acidic enzymes. Centrosomes organize microtubules as the primary MTOC during mitosis.
Exam Relevance
CSIR NET questions like this appear in Unit 2 (Cell Biology), emphasizing precise matching. Correct option (B) aligns with standard textbooks. Practice similar PYQs for retention.
