Species to expression of some of the pattern-forming genes in vertebrate limb bud: A. Lmx1b gene is expressed in dorsal mesenchyme B. Shh is expressed in the posterior region. C. […]
Tag: CSIR NET Life Science Previous Year Questions and Solution on Morphogenesis and Organogenesis in Animals
Tag: CSIR NET Life Science Previous Year Questions and Solution on Morphogenesis and Organogenesis in Animals
CSIR NET Life Science Previous Year Questions and Solution on Morphogenesis and Organogenesis in Animals
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Understanding Incorrect Statements in Tetrapod Limb Development: The Role of BMP in Cell Death and Hox Gene Patterns
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- November 9, 2025
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Which one of the following statements is NOT correct regarding the tetrapod limb development? (1) As the limb grows outward, the stylopod forms first, then the zeugopod and the autopod […]
HOXD13 Mutation and Its Impact on Limb Development: Understanding Syndactyly and Digital Malformations
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- November 9, 2025
- 3 Comments
Homeobox transcription factor (Hox proteins), play important roles in specifying whether a particular mesenchymal cell will become stylopod, zeugopod or autopod. Based on the expression patterns of these genes, a […]
How Retinoic Acid Proximalizes Blastema and Activates Hox Genes to Induce Complete Limb Regeneration in Axolotls
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- November 9, 2025
- 2 Comments
When a wrist blastema from a recently cut Axolotl forelimb is placed on a host hindlimb cut at the mid thigh level, it will generate only a wrist. The host […]
Role of BMP Signaling in Programmed Cell Death for Digit Separation During Tetrapod Limb Development
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- November 9, 2025
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The programmed cell death that separates the digits during a tetrapod limb development is dependent on which one of the following signaling pathways? (1) BMP (2) FGF (3) Wnt (4) […]
Mechanism of Limb Regeneration in Salamanders: Role of Blastema and Positional Specification
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- November 9, 2025
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46. Which one of the following statements regarding limb regeneration in Salamander is correct? (1) A normal limb is regenerated after amputation, irrespective of whether the cut was made below […]
Effect of Severing Nerve Supply on Newt Limb Regeneration: Importance of Nerves for Blastema Growth and Limb Outgrowth
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- November 9, 2025
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How will the regeneration of a newt limb be affected if the nerve supply is severed before amputation? (1) Partial regeneration will occur where only the proximal structures will be […]
Effect of Severe Nerve Severance on Newt Limb Regeneration: Role of Nerve Supply and Growth Factors
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- November 9, 2025
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What would be the effect on newt limb regeneration, if more than 90% of the nerve supply is severed before amputation? (1) The apical ectodermal cap stimulates growth of the […]
Key Aspects of Nerve Dependence and Pattern Regulation in Amphibian Limb Regeneration
Which of the following is true about amphibian limb regeneration? (A) It requires a minimum number of functional nerves. (B) The blastema of an amputated limb, if transplanted in the […]
Dose-Dependent Effects of Retinoic Acid on Positional Identity During Limb Regeneration
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- November 9, 2025
- 2 Comments
Dose-dependence of retinoic acid treatment supports the notion that a gradient of retinoic acid can act as a morphogen along the proximo-distal axis in a developing limb. Following are certain […]


