Q.26 Match List-I with List-II

Choose the correct answer from the options given below:

1. (A) – (IV), (B) – (I), (C) – (II), (D) – (III)
2. (A) – (I), (B) – (III), (C) – (II), (D) – (IV)
3. (A) – (I), (B) – (II), (C) – (IV), (D) – (III)
4. (A) – (II), (B) – (III), (C) – (IV), (D) – (I)

   Correct Answer: (D) (A) – (II), (B) – (III), (C) – (IV), (D) – (I)

   Leptin suppresses appetite in fat cells, while the other hormones regulate specific metabolic or calcium pathways. This matching tests endocrine functions key for GATE Life Sciences.

   Hormone-Function Matches

   A. Leptin → II. Suppresses appetite
   Produced by adipocytes, leptin signals satiety to the hypothalamus, reducing hunger via NPY inhibition and POMC activation.

   B. Pancreatic polypeptide → III. Inhibits somatostatin secretion
   From F cells in pancreas, it curbs somatostatin (which inhibits insulin/glucagon), aiding post-meal regulation [ from prior context].

   C. Parathyroid hormone → IV. Promotes formation of calcitriol
   PTH stimulates kidney 1α-hydroxylase to convert 25(OH)D to active calcitriol (1,25(OH)2D), boosting calcium absorption.​

   D. Epinephrine in skeletal muscle → I. Conversion of glycogen to glucose-1 phosphate
   Adrenaline activates glycogen phosphorylase in muscle, breaking glycogen to glucose-1-phosphate for rapid energy.​

   Option Analysis

   Option 1: (A)–(IV), (B)–(I), (C)–(II), (D)–(III)
   Wrong: Leptin doesn’t form calcitriol; PTH does. Mismatches B-D.

   Option 2: (A)–(I), (B)–(III), (C)–(II), (D)–(IV)
   Wrong: Leptin isn’t glycogen breakdown; epinephrine is. PTH not appetite suppressor.

   Option 3: (A)–(I), (B)–(II), (C)–(IV), (D)–(III)
   Wrong: Leptin not glycogen; PP not appetite. D mismatched.

   Option 4: (A)–(II), (B)–(III), (C)–(IV), (D)–(I)
   Correct: All align precisely with functions above.

   Hormone	Correct Match	Key Action
   Leptin	II	Appetite suppression ​
   Pancreatic polypeptide	III	Inhibits somatostatin
   Parathyroid hormone	IV	Calcitriol formation
   Epinephrine (muscle)	I	Glycogenolysis ​

   Introduction to Hormone Function Matching GATE Life Sciences

   Master hormone function matching GATE Life Sciences questions like Leptin (appetite suppression), Parathyroid hormone (calcitriol promotion), and Epinephrine in skeletal muscle (glycogen conversion). This PYQ tests precise endocrine roles for exams.​

   Leptin: Appetite Regulator

   Leptin from fat signals brain to suppress appetite, preventing overeating via hypothalamic pathways.​

   Pancreatic Polypeptide Role

   Inhibits somatostatin from delta cells, fine-tuning pancreatic hormone balance post-meal.

   Parathyroid Hormone and Calcitriol

   PTH activates vitamin D to calcitriol, enhancing gut calcium uptake for bone health.

   Epinephrine in Skeletal Muscle

   Triggers glycogen to glucose-1-phosphate, fueling fight-or-flight via phosphorylase activation.​

   GATE Exam Strategy

   Memorize pairings: Leptin-II, PP-III, PTH-IV, Epi-I. Practice matchings for quick scoring.​