25. Scientists usually find difficulty in identifying the exact transcription termination site in eukaryotes because (1) immediately following termination of transcription, the 3′ end is polyadenylated (2) The 3′ end […]
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Housekeeping Gene Promoters with CpG Islands Remain Expressed Despite CpG Methylation in Mammals
24. In mammals CG rich sequences are usually methylated at C, which is a way for making genes for silencing. Although the promoters of housekeeping genes are often associated with […]
Eukaryotic Transcription by RNA Polymerase III
23. Following statements were made with respect to transcription in eukaryotes: A. RNA polymerase III synthesizes mRNAs in the nucleoplasm B. The target promoter for RNA polymerase Ill is usually […]
Viral Protein X Inducing Cellular Gene Promoter Activity Without Direct DNA Binding
22. A non-enzymatic viral protein X was found to be inducing a cellular gene promoter activity. Although no in vitro DNA binding activity could be identified with X protein, it […]
Transcription Initiation Steps in Bacteria and Eukaryotes
Transcription Initiation Steps in Bacteria and Eukaryotes The initiation of transcription is a complex process involving promoter recognition, conversion of the initiation complex from closed to open form, abortive initiation […]
TFIIH Mutation Impact on Transcription and DNA Repair
20. In order to study the transcription factor TFIIH. It was cloned from a large number of human subjects. Surprisingly, the subject having mutation in TFIIH, also showed defects in […]
TATA Binding Protein (TBP) Component of transcription factor TFIID
19. Which one of the following statements about TATA Binding Protein (TBP) is NOT true? (1) It is a component of transcription factor TFIID. (2) TBP recognizes the TATA element […]
TBP TATA Binding Protein universal basal transcription factor
18. Genetic studies demonstrated that TBP mutant cell extracts are deficient in transcription of genes from all three promoters viz. class I, II and III. Following statements describe characteristic features […]
Promoters for RNA Polymerase III: Location and Function
17. Promoters for RNA polymerase III are located at (1) +1 to +10 (2) -35 to -10 (3) With in transcribed sequence (4) More than 100 by upstream The correct […]
Eukaryotic RNA Polymerase Transcribes tRNA Genes
16. Which eukaryotic RNA polymerase transcribes t-RNA genes? (1) RNA polymerase I (2) RNA polymerase II (3) RNA polymerase III (4) DNA polymerase I Which Eukaryotic RNA Polymerase Transcribes tRNA […]


