6.An antibiotic that resembles the 3′ end of a charged tRNA molecule is: (1) Streptomycin(2) Sporsomycin (3) Puromycin (4) Tetracycline
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CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Puromycin Mechanism of Action: True Statements and Biological Insights
5. Puromycin is an antibiotic used to inhibit protein synthesis. Given below are few statements about the antibiotic. A. It enters the E-site of the ribosome where it prevents the […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Understanding trp-lac Fusion Operon Behavior: Regulation and Expression in E. coli
41. In a strain of E.coli, a fusion between the lac and trp operon took place and the new locus structure is shown below. The strain lacks the wild type […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
How Puromycin Blocks Translation: Mechanism, Molecular Action, and Biological Significance
4. Puromycin blocks translation. Mode of action of drug puromycin is (1) binds to A site and leads to premature termination (2) stops peptidyl transferase activity (3) Binds EF-TU-GTP and […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Transcriptional Regulation of the trp Operon by Tryptophan: Mechanism and Biological Significance
40. Transcriptional regulation of trp operon by tryptophan involves binding of tryptophan to (1) the repressor protein and inhibition of transcription by its interaction with the operator region. (2) RNA […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Which Antibiotic Causes Premature Termination of Translation in Bacteria? Mechanism, Uses, and Insights
3. Which antibiotic is responsible for premature termination of translation in bacteria? (1) Tetracycline (2) Choloramphenicol (3) Penicillin (4) Puromycin Translation is a fundamental biological process in all living cells, […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Bidirectional Promoter Regulation in E. coli: How Loss of Regulatory Protein Binding Alters Reporter Gene Activity
39. A construct (shown below) was generated to access the activity of bidirectional promotor (A and B) which has a common regulatory DNA element (X). The construct was used to […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Which Antibiotic Inhibits Protein Synthesis in Chloroplasts? Mechanism and Key Insights
2. Among the following which antibiotic will inhibit protein synthesis in chloroplast? (1) Cyclohexamide (2) Chloromphenicol (3) Rifamcin (4) Ricin Chloroplasts, the green energy factories of plant cells, are unique […]
CSIR NET Life Science Previous Year Questions and Solution on EUKARYOTIC GENE REGULATION
Effect of trpL Codon Mutations on Tryptophan Synthetase Activity in E. coli: Graph Interpretation and Molecular Insight
38. The following graph represents the expression of tryptophan synthetase (TS) in E. coli cells in absence ( ) or presence ( ) of tryptophan in the medium If the […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Chloramphenicol: Mechanism of Action, Ribosomal Binding, and Clinical Implications
1. Chloramphenicol is a “broad-spectrum” antibiotic which inhibits protein synthesis in prokaryotes. Given below are a few statements regarding the mode of action of chloramphenicol. A. Chloramphenicol inhibits the peptidyl-transferase […]
