How Translesion Synthesis (TLS) DNA Polymerases Reduce Replicative Fidelity by 100-Fold DNA replication fidelity is critical for genome stability. However, when DNA damage blocks replicative polymerases, cells employ specialized DNA […]
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CSIR NET Life Science Previous Year Questions and Solution on DNA REPAIR AND RECOMBINATION
Key Steps of Double-Strand Break Repair (DSBR) Model in Homologous Recombination Explained
Following statements are made about double-strand break repair (DSBR)model of homologous recombination: A. Process of DSBR recombination is triggered by introducing a double-strand break in a DNA duplex B. In […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPAIR AND RECOMBINATION
RuvB Protein Catalyzes Branch Migration Activity in the Holliday Junction During DNA Recombination
Which one of the following proteins catalyzes branch migration activity in Holliday Junction? (1) Spo11 (2) RuvB (3) Zip1 (4) RuvC Which Protein Catalyzes Branch Migration Activity in the Holliday […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPAIR AND RECOMBINATION
Roles of E. coli RecA and DnaB Genes: DNA Repair, SOS Response, and DNA Unwinding Explained
In E. coil, recA gene is involved in recombination as well as repair and dnaB gene is involved in unwinding of DNA double strands during replication. Which of the following […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Regulation of Replication Initiation in E. coli: Which Statements About SeqA, DnaA, ATP/ADP Ratio, and Hda Are Incorrect?
30. In all organisms, it is critical that replication initiation be tightly controlled to ensure that chromosome number and cell number remain appropriately balanced. Given below are several statements regarding […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Which Statements About DNA Replication Initiation Regulation in E. coli Are Incorrect? Roles of SeqA, DnaA, ATP/ADP Ratio, and Hda Protein
In all organisms, it is critical that replication initiation be tightly controlled to ensure that chromosome number and cell number remain appropriately balanced. Given below are several statements regarding regulation […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPAIR AND RECOMBINATION
Recombination Repair Explained: Why Topoisomerase II Does Not Catalyze Homologous Recombination
The homologous genetic recombination is a DNA repair process referred to as recombination repair. Which one of the following statements is INCORRECT for recombination repair? (1) DNA polymerase III stalls […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPAIR AND RECOMBINATION
Meiotic Double-Strand Break Repair in Saccharomyces cerevisiae Uses Homologous Chromosome as Template
Repair of double strand break made during meiosis in the yeast Saccharomyces cerevisiae (1) occurs mostly by non-homologous end joining. (2) occurs mostly using the sister chromatid as a template. […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
How DNA Polymerase Reduces Replication Errors: The Critical Role of 3′→5′ Proofreading Activity
While replicating DNA, the rate of mis-incorporation by DNA polymerase is 1 in 105 nucleotides. However, the actual error rate in the replicated DNA is 1 in 109nucleotides incorporated. This […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Helicase Loading in Eukaryotic DNA Replication Occurs During G1 Phase: Mechanism and Regulation Explained
In eukaryotic replication, helicase loading occurs at all replicators during (1) Go phase (2) G1 phase (3) S phase (4) G2 phase Introduction DNA replication in eukaryotic cells is […]
