Genetic disorder Xeroderma pigmentosum is due to defect in (1) Base excision repair mechanism (2) Nucleotide excision repair mechanism (3) Direct repair mechanism (4) DNA replication mechanism Xeroderma Pigmentosum: A […]
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CSIR NET Life Science Previous Year Questions and Solution on DNA REPAIR AND RECOMBINATION
UvrABC Repair Mechanism Repairs DNA Damage Caused by Bulky Chemical Adducts
The ‘Uvr ABC’ repair mechanism is involved in repairing (1) missing bases. (2) strand break. (3) cross linked strands. (4) DNA damage caused by “bulky” chemical adducts. The UvrABC Repair […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
How Dideoxycytidine Triphosphate and Dideoxy CMP Affect DNA Synthesis Rate in In Vitro Reactions
Double stranded DNA replicates in a semi-conservative manner. In an in vitro DNA synthesis reaction, dideoxyCTP and, dideoxy CMP were individually added in excess (in separate reaction tubes) in addition […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
How DNA Polymerase I Synthesizes DNA on Different DNA Substrates: Single-Stranded, Nicked, Linear, and Circular Molecules
In a cell free extract containing DNA polymerase I, Mg2+, dATP, dGTP, dCTP and dTTP3H), the following DNA molecules were added: Single stranded closed circular DNA moleculecontaining 824 nucleotides. Single […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPAIR AND RECOMBINATION
Pyrimidine Dimers in Eukaryotic Cells Are Repaired by Nucleotide Excision Repair
Pyrimidine dimers in eukaryotic cells are repaired by (1) nucleotide excision repair (2) SOS pathway (3) base excision repair (4) mismatch repair Pyrimidine Dimers in Eukaryotic Cells Are Repaired by […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPAIR AND RECOMBINATION
Which Mutagen Induces Thymine Dimer Formation in DNA? Understanding UV Radiation Effects
Among the following which mutagen induces formation of thymidine dimmers in DNA (1) UV rays (2) Ethyl methyl sulphate (3) Nitrous oxide (4) Ethidium bromide Which Mutagen Induces Formation of […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Which Statement About DNA Replication Is Incorrect? Insights into Replication Continuity, Origins, and Methylation
Which one of the following statements about DNA replication is INCORRECT? (1) Once DNA replication commences, it always continues uninterrupted until the entire process is complete. (2) Eukaryotic genomes replicate […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Which Statement About DNA Replication Is Incorrect? Clarifying Leading and Lagging Strand Synthesis
Which one of the following statements about DNA replication is INCORRECT? (1) During DNA replication, When adjacent bidirectional forks converge, the lagging strandwill meet the leading strand of the same […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPAIR AND RECOMBINATION
MutY and Alternative Repair Pathways: How E. coli Survives Without This Key DNA Glycosylase
Aguanine (G) base in DNA is susceptible to modification to 8-oxo-G because of oxidative damage. If the modified G residues are not removed by a DNA glycosylase (Mut M or […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Understanding DNA Polymerase’s Selectivity: Why rNTPs Are Incorporated Into DNA at Much Lower Rates Than dNTPs
Although ribonucleoside triphosphates (rNTPs) are present at approximately IO-fold higher concentration than deoxyribo-nucleoside triphosphates (dNTPs) in the cell but they are incorporated into DNA at a rate that is more […]
