42. Localized increases in the cytosolic level of free Ca2+ arecritical to its function as second messenger. Calmodulin,a small cytosolic protein, mediates many cellular effectsof Ca2+. Which of the following […]
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CSIR NET Life Science Previous Year Questions and Solution cell biology
How IP3 Production Elevates Intracellular Calcium During Signal Transduction
41. Effect of production of during Signal transduction pathway is (1) Closure of Ca2+ channel in ER (2) Increase in intracellular Ca2+ level (3) Increase of extracellular Ca2+ level (4) […]
CSIR NET Life Science Previous Year Questions and Solution cell biology
How Intracellular Calcium Is Released: The Role of IP3 and Related Mechanisms
40. Release of intracellular calcium is due to (1) absence of PIP2 hydrolysis. (2)rapiddephosphorylation of IP3 (3) retention of DAG in the cytosol. (4) activation of IP3 receptors. Introduction Calcium […]
CSIR NET Life Science Previous Year Questions and Solution cell biology
Essential Cofactors for Protein Kinase C (PKC) Activation: Role of Phosphatidylserine, Ca²⁺, and Diacylglycerol
39. In the context of signaling, the enzyme protein kinase C (PKC) depends on multiple molecules for its complete activation. This activation depends on the presence of: A. phosphatidylserine at […]
CSIR NET Life Science Previous Year Questions and Solution cell biology
Identifying the Receptor Without Tyrosine Kinase Activity in Its Cytoplasmic Domain: Asialoglycoprotein Receptor Explained
38. The cytoplasmic domain of the receptor of which of the following proteins does NOT function as tyrosine kinase? (1) Epidermal growth factor (2) Platelet derived growth factor (3) Insulin […]
CSIR NET Life Science Previous Year Questions and Solution cell biology
Activation Mechanism of Receptor Tyrosine Kinases: The Crucial Role of Phosphorylation
37. Activity of Receptor tyrosine kinase is initiated by (1) Phosphorylation (2) dephosphorylation (3) Methylation (4) Acetylation Activation of Receptor Tyrosine Kinases (RTKs): Phosphorylation as the Initiating Event Introduction Receptor […]
CSIR NET Life Science Previous Year Questions and Solution cell biology
Distinguishing GPCRs from Other Receptors: Clarifying Misconceptions
36. Which one of the following is not a G-protein coupled receptor? (1) Epinephrine receptor (2) Transferrin receptor (3) Glucagon receptor (4) Thyroid stimulating hormone receptor Introduction: G-protein coupled […]
CSIR NET Life Science Previous Year Questions and Solution cell biology
Key Facts and Common Misconceptions in the Inositol Phospholipid Signaling Pathway
35. Although a majority of G protein-coupled receptors (GPCRs) act through adenylyl cyclase, many of them (GPCR) exert their effects by activating the plasma membrane-bound enzyme phospholipase C-β (PLC-β). These […]
CSIR NET Life Science Previous Year Questions and Solution cell biology
Regulation of Monomeric G Proteins: Understanding the Roles of GEFs and GAPs in Ras Signaling
34. The cycling of monomeric G proteins, such as Ras, between active and inactive states is aided by accessory proteins that bind to the G protein and regulate its activity. […]
CSIR NET Life Science Previous Year Questions and Solution cell biology
Key Facts and False Statements About G-Protein Coupled Receptors (GPCRs)
33. G protein-coupled receptors (GPCRs) are used to detect and respond to many different types of signals, including neurotransmitters, hormones involved in glycogen and fat metabolism and even photons of […]
