Blog

22. The mode of action of cholera toxin in causing diarrhoea is by: (1) inactivating Gi protein. (2) continuousactivation of adenylyl cyclase. (3) locking GS protein in an inactive state. […]

21. In small intestine, cholera toxin acts by (1) active absorption of NaCl (2) activation of GTPase (3) inhibition of adenylyl cyclase (4) ADP-ribosylation of the G-protein Introduction Cholera toxin, […]

In the above signaling cascade, which of the following molecules is denote by ‘B’? (1) single-pass.      (2) three-pass (3) five-pass.         (4) Seven-pass. Understanding the Structure of Cellular Receptors: Identifying ‘B’ […]

  (JUNE 2019) 12- Following are the list of some cellular receptors (Column X) and With possible functional characteristics (Column Y): Column X Column Y A. Asialoglyco protein receptor (i) […]

The table below summarizes the key signaling pathways that orchestrate development, their receptors, transcription effectors and output. SIGNALING PATHWAY RECEPTOR TRANSCRIPTIONAL EFFECTOR OUTPUT A Wnt Thick veins β-catenin Patterning B […]

Which one of the following combinations is the correct pairing of ligands with their receptors? (i) FGF (a) Patched (ii) Hedgehog (b) Frizzled (iii) Wnt (c) Receptor tyrosine kinase (1) […]

8. Some T lymphocytes respond to antigen stimulation by synthesizing a growth factor that causes T cell proliferation thereby increasing the responsive T lymphocytes resulting in amplification of the immune […]

7. Which of the following is NOT a second messenger? (1) cyclic GMP (2) Diacylglycerol (3) Inositol triphosphate (4) Phosphatidyl inositol Introduction Cell signaling involves complex pathways where extracellular signals […]

6. The second messenger, which opens calcium ion pores in endoplasmic reticulum and plasma membrane is (1) Diacylglycerol (2) cAMP (3) Phosphatidyl inositol bisphosphate (4) Inositol triphosphate Inositol Triphosphate and […]

5. Which of the following signaling molecules enters the cell to initiate its action? (1) Transferrin      (2) Insulin (3) Glucagon       (4) Thyroxine Overview of Signaling Molecules and Their Entry Modes […]