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32. The signal transduction pathway involved in glycogen metabolism triggered in the liver by the hormone epinephrine involves the following steps: (A) Activation of G protein (Gαβγ) by the activated […]

31. Glucose is mobilized in muscle when epinephrine activates Gas. In an experiment in which muscle cells were stimulated with epinephrine, glucose mobilization was observed even after withdrawal of epinephrine. […]

30. In cells having G protein coupled receptor, inhibition of protein kinase A by siRNA technology led to diminished transcription of androgen binding protein (ABP) and CREB protein. Addition of […]

29. G-protein coupled receptors (GPCR) consist of three protein subunits  α, β and γ. In unstimulated state, a- subunit is GDP bound and GPCR is inactive. When GPCR gets activated. […]

28. Which one of the following events NEVER activates the G-protein coupled receptor for sequestering Ca2+ release? (1) Interaction of bind in to sperm receptors. (2) Activation of Frizzled by […]

27. Which one of the following statements about receptor – enzyme isFALSE? (1) A receptor enzyme has an extracellular ligand binding domain, a transmembrane domain and an intracellular catalytic (enzyme) […]

26. The second messenger CAMP, synthesized by adenylyl cyclase transduces a wide variety of physiological signals in various cell types in mammalian cells. Most of the diverse effects of cAMP […]

25. In signal transduction trimeric G protein with α,β and γis involved. Which subunit will activate adenylate cylase (1) α subunit        (2) β subunit (3) γ  subunit       (4) All three […]

24. C-AMP is directly involved in regulation of (1) Adenylate cyclase (2) Protein kinase A (3) Phosphofrucotokinase (4) ATP Cyclic AMP (cAMP) and Its Role in Cellular Regulation Introduction Cyclic […]

23. Vibrio cholrae causes diahorrea by (1) Closing ion channels (2) Constitutive expression of adenylate cyclase (3) Closing absorption of water from gut epithelium (4) Destroys cells of intestinal lining […]