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38. Which of the following cellular communications shown below will override the process of normal development and lead to cancer? (1) B and C                                                   (2) A and C (3) A […]

A patient with ER+/PR+ breast cancer was cured with a drug ‘T’ whereas a second patient, did not respond to ‘T’. Which one of the following is the best therapy […]

A breakthrough in cancer therapy is expected where T- cells are taken from a patient are modified in the laboratory to attack cancer cells before re-infusion in the patient. These […]

An important role of Fas and mediate elimination of tumor cells by killer lymphocytes. In a study of 35 primary lung and colon tumors, half the tumors were found to […]

Cancer causing genes can be functionally classified into mainly three types: (i) genes that induce cellular proliferation, (ii) tumor suppressor genes, (iii) genes that regulate apoptotic pathway. Epstein-Barr virus that […]

33. Tumor cells were isolated from a breast cancer patient. These cells were injected into nude mice and they were divided into four groups. Group 1 received EGF receptor-conjugated with […]

While testing the effect of several potent anti-cancer compounds on cycling human oral cancer cells, a student observed that a major percentage of cells showed dose-deep cell death after 12 […]

After successive surgery and chemotherapy, the tumor of a breast cancer patient subsided. However after almost 5 years, the tumor relapsed in a more aggressive manner and did not respond […]

A patient with breast cancer was given a dose of radiation along with chemotherapy and was apparently cured of the tumor. After five years, a tumor was noticed in the […]

29. Cellular level of tumour suppressor protein p53 is maintained by the ubiquitin ligase protein, Mdm2. Over expression of Mdm2 was found to convert a normal cell into cancer cells […]