The mode of action of the anticancer drug methotrexate is through its strong competitive inhibition on (1) dihydrofolate reductase (2) thymidine synthase. (3) thymidine kinase. (4) adenylate cyclase. Final Answer The […]
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Cancer
Types of Mutations that Activate Oncogenes: Understanding Gain of Function Mutations
17. The mutation in an oncogene falls under which of the following classes? (1) Loss of function mutation (2) Frame shift mutation (3) Gain of function mutation (4) Dominant negative […]
Cancer
Key Differences Between Normal and Transformed Cells: Immortality and Contact Inhibition
The main difference between normal and transformed cells (1) immortality and contact inhibition (2) shorter generation time and cell mobility (3) apoptosis and tumour suppressor gene hyper- function. (4) inactivation […]
Cancer
What is a Tumor Suppressor Protein? Definition and Key Functions
A tumour suppressor protein (1) is one whose function brings about regression of a tumour (2) one where mutations are shown to cause or are associated with tumour. (3) is […]
Cancer
Which Oncogene-Protein Match is Incorrect? Clarifying erbA, erbB, ras, and fos Functions
Out of the following matches of oncogenes with the proteins that each specifies, which one is incorrect? (1) erbA – thyroid hormone receptor. (2) erbB – epidermal growth factor receptor. […]
Cancer
Use of Monoclonal Antibodies against erb-B2 Receptor in Breast Cancer Treatment
In which cancer treatment monoclonal antibodies against erb-B2 receptor are used? (1) Breast (2) Oral (3) Prostrate (4) Lung The monoclonal antibodies against the erb-B2 receptor (also known as HER2 […]
Cancer
First Successful Cancer Vaccine: The Cervical Cancer HPV Vaccine
12. First successful Vaccine against cancer has been prepared for (1) Oral cancer (2) Cervical cancer (3) Breast cancer (4) Colon cancer The first successful vaccine against cancer is […]
Cancer
Which Oncogene-Protein Match is Incorrect? Understanding erbA, erbB, ras, and fos
Which of the following matches of oncogene-protein product is NOT correct? (1) erbA→Thryoid hormone receptor (2) erbB →Epidermal Growth Factor receptor (3) ras→Guanine nucleotide binding protein with GTPase activity (4) […]
Cancer
Which Event Does NOT Lead to Cancer Cell Transformation? Understanding Oncogenes, Tumor Suppressors, and DNA Repair Genes
10. Which of the following events will NOT usually lead to transformation of a normal cell into a cancer cell (1) Gain of function of oncogenes (2) Loss of function […]
Cancer
What is an Oncogene? Definition and Role in Cancer Development
Which one of the following best defines an oncogene? (1) An oncogene never codes for a cell cycle protein, which promotes cell proliferation. (2) Oncogenes are always involved in inherited […]
