Factor IX is essential for blood clotting. Deficiency of Factor IX could be corrected by delivering factor IX gene using viral vectors. In an experiment the gene for Factor IX […]
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CSIR NET Life Science Previous Year Questions and Solution on applied biology
Choosing the right promoter for macrophage‑specific transgene expression
One aims to find out the role of a gene product in macrophages by using a transgenic mouse expressing the genes under a promoter. Which of the following is the […]
CSIR NET Life Science Previous Year Questions and Solution on applied biology
Stem cell–based strategies to regenerate functional bone across large defects
Stem cell therapies are being used in regenerative medicine like forming new adult bone, which usually does not regrow to bridge wide gaps. Successful attempts have now been made in […]
CSIR NET Life Science Previous Year Questions and Solution on applied biology
Identifying the false statement about modern gene therapy
Gene therapy is a promising tool for addressing several diseases in humans. With respect to the above, which one of the following statements is FALSE? (1) Gene therapy involves the […]
CSIR NET Life Science Previous Year Questions and Solution on applied biology
Which human stem cells are actually used in somatic cell gene therapy?
Following are the different ways of obtaining human stem cells- (A) Cells from morula are dispersed and cultured to give rise pluripotent stem cells. (B) Isolated inner cell mass of […]
CSIR NET Life Science Previous Year Questions and Solution on applied biology
Safest stem‑cell strategy for liver regeneration using patient‑specific iPS cells
Stem cells are widely used for their regenerative property and capacity to differentiate into different lineages. A person with a damaged liver approaches a stem cell therapist. Which of the […]
CSIR NET Life Science Previous Year Questions and Solution on applied biology
Explaining transient increase and recovery of muscle tone after caudate lesion
The muscle tone was increased after electrolytic lesion of the caudate nucleus in a cat. The muscle tone decreased within seven days. The following explanations were given by the researcher. […]
CSIR NET Life Science Previous Year Questions and Solution on Animal Cell Culture and Transgenic Animals
Maintaining a line of heterozygous transgenic mice
Inbreeding for 5 generations led to production of homozygous transgenic mice. However, these homozygous males or females were infertile. Which of the following approach is most preferable and economical to […]
CSIR NET Life Science Previous Year Questions and Solution on Animal Cell Culture and Transgenic Animals
Why DMEM turns yellow in liver cell culture
A student added DMEM culture medium which was pink in colour to growing liver cells. Three days later the medium colour was yellow. This indicated (1) change in cell morphology […]
CSIR NET Life Science Previous Year Questions and Solution on Animal Cell Culture and Transgenic Animals
Method to detect mycoplasma contamination in mammalian cell cultures
Which is best method for checking mycoplasma contamination in a mammalian cell line? (1) Southern Hybridization (2) ELISA (3) PCR (4) Western Hybridization The best method is (3) PCR. Why PCR […]
