16. Segmentation genes in Drossophila are divided into three groups (gap, pair rule and segment polarity) based on their mutant phenotype. Below are some of the major genes expressed in […]
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Armadillo: The Drosophila Homolog of β-Catenin and Its Role in Development
The homologue of β-catenin in Drosophila is (l) Fushi tarazu (2) Engrailed. (3) Armadillo (4) Cubitus interruptus. In Drosophila melanogaster, the protein Armadillo serves as the homolog of the mammalian […]
Understanding Antennapedia Mutations and Their Impact on Drosophila Development
Antennapedia protein expresses in the thoracic segment of the fly and not in the head region. However, a dominant mutation of Antennapedia replaces antenna with leg-like structure. The following statements […]
Maternal Somatic Cell Fate Determination Preceding Embryonic Fate: Developmental Events Overview
In which one of the following developmental events, the fate of maternal somatic cell is determined first, which then the fate of the developing embryo? (1) 1.The specification of primary […]
Accurate Gene-Phenotype Matching for Maternal Effect Genes in Drosophila Anterior-Posterior Polarity
Maternal effect genes are extremely important in establishing the anterior-posterior polarity of the Drosophila embryo. Mutant phenotypes arise when genes of this family are mutated. The following table enlists genes […]
Noggin: A Key BMP Inhibitor That Rescues Dorsal Structures in Ventralized Xenopus Embryos
Which one of the following mRNAs is a BMP inhibitor and can rescue the dorsal structures of ventralized Xenopus embryo when injected into it? (1) beta-catenin (2) Noggin (3) Disheveled […]
Impact of Posterior Injection of Bicoid mRNA on Drosophila Embryonic Patterning
If an early cleavage stage wild type Drosophila embryo is injected with bicoid mRNA at the posterior pole then (1) head structures develop at posterior pole, while the same is […]
Understanding Cell Fate Specification and Cleavage Patterns in Animal Development
Following statements are made regarding animal development: A. The cell is first specified towards a given fate, suggesting that it would develop into this cell type, even in a neutral […]
Comprehensive Insight into Anterior-Posterior Patterning Genes in Drosophila Embryo
The following statements were made regarding the patterning of anterior-posterior body plan of Drosophila: A. Microinjection of bicoid mRNA in the middle of a bicoid-deficient embryo leads to formation of […]
Phenotypic Outcomes of Bicoid mRNA Injection in Wild Type and Mutant Drosophila Embryos
9. Three embryos, X (wild type), Y (mutant for bicoid) and Z (mutant for nanos) were injected with bicoid mRNA in their posterior pole at early cleavage stage. What would […]


