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During wing development in chick, if Apical Ectodermal Ridge (AER) is removed, the limb development ceases, on the other hand placing leg mesenchyme directly beneath the wing AER, distal hindlimb […]

In the context of the proximal-distal growth and differentiation of a tetrapod limb following experiments were visualized (A) If the apical ectodermal ridge (AER) is removed at any time during […]

A set of experiments that were carried out to demonstrate the effect of Apical Ectodermal Ridge (AER) of the chick limb bud on the underlying mesenchyme are enlisted below, along […]

The proximal distal growth and differentiation of the tetrapod limb bud are made possible by a series of interactions between the apical ectodermal ridge (AER) and limb bud mesenchyme directly […]

During vertebrate limb development, a specialized ectodermal structure, called Apical Ectodermal Ridge (AER), forms at the dorso-ventral ectodermal boundary at the distal tip of the developing limb bud. The following […]

What would happen as a result of a transplantation experiment in a chick embryo where the leg mesenchyme is placed directly beneath the wing apical ectodermal ridge (AER)? (1) Distal […]

Apical ectodermal ridge induction is essential tetrapod limb development. Which of the following is NOT essential for the formation of a functional limb? (1) Tbx genes and Wnt (2) Androsterone […]

Over-expression of a dominant negative FGF receptor during amphibian development would prevent formation of (1) trunk and tail (2) head and trunks. (3) trunk and fore limbs. (4) head and […]

In mice, the gene encoding Tbx5 is transcribed in limb fields of the forelimbs, while the genes encoding lslet1, Tbx4 and Pitx1 are expressed in presumptive hind limbs. Following statements […]

Which one of the following statements regarding limb development in mice is true? (1) The gene encoding Tbx5 is transcribed in the limb fields of the hindlimbs. (2) The gene […]