Of the signaling processes involved in cellular movement or cytoskeletal changes, some pathways are directly related to the regulation of cytoskeletal dynamics, cell motility, and shape, while others are not primarily involved in these functions.

Typically involved signaling processes include:

• Rho family GTPases (Rho, Rac, Cdc42) pathways that regulate actin cytoskeleton reorganization and cell motility.

• PI3K/Akt signaling involved in directional sensing and motility.

• MAP kinase pathways that affect cytoskeletal dynamics and cell migration.

• Calcium signaling which influences actin dynamics and cellular contractility.

A process that is generally NOT involved in cellular movement or cytoskeletal changes would be signaling pathways not linked to cytoskeletal regulation or motility, such as those primarily involved in other cellular functions like:

• Pathways related to DNA replication and repair,

• Metabolic control pathways without specific links to cytoskeletal dynamics,

• Classic hormone receptor signaling pathways unrelated to cytoskeleton rearrangement.