- Junctions which tether cytoskeletal filaments inside the cell are known as
(1) anchoring junctions (2) occluding junctions
(3) channel forming junction (4) signal – relay junction
correct answer is:
(1) (A) and (B)
Explanation:
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(A) is incorrect: Tight junctions are not cell-cell junctions connecting intermediate filaments between cells. Tight junctions are occluding junctions that seal the space between cells to prevent leakage of substances through the paracellular pathway.
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(B) is incorrect: Desmosomes are cell-cell anchoring junctions connecting intermediate filaments between adjacent cells, not cell-matrix anchoring junctions connecting actin filaments to the extracellular matrix.
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(C) is correct: Gap junctions are channel-forming junctions that allow the passage of small water-soluble molecules from cell to cell.
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(D) is correct: Tight junctions are occluding junctions that seal the gap between two cells.
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(E) is correct: Hemidesmosomes are cell-matrix anchoring junctions connecting intermediate filaments inside the cell to the extracellular matrix.
Summary Table
| Junction Type | Characteristic | Correctness |
|---|---|---|
| Tight junctions (A) | Connect intermediate filaments between cells | Incorrect |
| Desmosomes (B) | Cell-matrix anchoring connecting actin to ECM | Incorrect |
| Gap junctions (C) | Channel-forming junctions for small molecule passage | Correct |
| Tight junctions (D) | Occluding junctions sealing cell-cell gaps | Correct |
| Hemidesmosomes (E) | Cell-matrix anchoring connecting intermediate filaments | Correct |
Conclusion
Statements (A) and (B) are false as they incorrectly describe tight junctions and desmosomes. The other statements accurately describe the roles of the respective cell junctions.
1 Comment
Kajal
November 7, 2025A and B