105. K-tuple method is associated with: (a) Dot matrix , (b) Dynamic programming , (c) Multiple sequence alignment, (d) Sequence similarity Introduction In bioinformatics, sequence analysis plays a crucial role […]
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Understanding the Conversion of Proto-Oncogenes to Oncogenes
Which of the following process does NOT contribute to conversion of a proto-oncogene to oncogene? 1. de-activating mutation in tumor suppressor 2. activating mutation in proto-oncogene 3. increased expression of […]
Understanding In Vitro ADMET Analysis: What It Can and Cannot Reveal
104. The in vitro ADMET analysis cannot provide information about: (a) Cytochrome P450 inhibition, (b) Adverse reaction to the drug , (c) Blood-brain barrier penetrability, (d) Metabolic Stability, Introduction ADMET […]
Choosing the Right Scoring Matrix in BLAST for Sequence Similarity Searches
103. A protein sequence was isolated from a novel source. During an initial sequencesimilarity search through BLAST, no homologous sequence was identified. A furtherBLAST search should be run by changing […]
Understanding Fermentation: A Unique Energy Generation Process in Microbes
An energy generatioin process in which organic compounds act as both electron donors and terminal electron acceptor in a microbe is called 1. photosynthesis 2. biomass formation process 3. aerobic […]
Understanding CASP: How It Evaluates Protein Structure Prediction Techniques
102. CASP judges one of the following: (a) Experimental techniques of structure determination, (b) Quality of protein structures, (c) Suitability of drug , (d) Techniques of protein structure prediction Introduction: […]
Factors Affecting Exit Cell Concentration in a Chemostat
133. In a chemostat, which one of the following would increase the exit cell concentration? (1) Increase in inlet substrate concentration (2) Increase in dilution rate (3) Increase in inoculum […]
The Role of Flippase Enzyme in Genome Engineering: Key Functions and Applications
During genome engineering process, the role of flippase enzyme in the next round of modification in the target gene is to 1. add frt sequence 2. remove frt sequence 3. […]
Understanding Sequence Alignment with Needleman-Wunsch Algorithm: Best Score Calculation
101. Two sequences PLAVAV and PLLV were aligned using Needliman-Wunsch algorithm with the scores, match = 1, mismatch = -1, gap initiation = -1, gap elongation = -2. The alignment […]
Understanding the Impact of Microbial Cell Yield on Substrate Consumption in Bioprocesses
132. In a bioprocess, assume that only cell mass is formed. Due to a variation in process conditions, if the microbial cell yield has halved, what would be the rate […]


