The challenges laced by aminoacyl tRNAsynthetase in selecting the correct amino acid is more daunting than its recognition of the appropriate tRNA. In case of amino acids with similar structures […]
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CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Aminoacyl-tRNA Synthetases Attach Amino Acids to Either 2′-OH or 3′-OH of tRNA’s Terminal Adenosine
The aminoacyl-tRNAsynthetases (AARSS) in an organism have evolved to catalyseaminoacylation of their cognate tRNAs (1) either at the 3′-OH or 2′-OH positions of the adenosine at the CCA end. (2) […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Key Factors Regulating Fidelity of DNA Replication: Proofreading, dNTP Balance, and Mismatch Repair
The following statements refer to factors regulating the fidelity of DNA replication. The 5′ to 3′ exonuclease activity of the replicative DNA polymerase. Imbalanced intracellular concentrations of the four dNTPs. […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Predicting mRNA Sequences from Protein Sequences: The Role of Codon Usage and Genetic Code Degeneracy
Amino acid sequence for a protein is known, we canestimate the sequence of m-RNA coding that protein- (1) Precisely (2) Can’t be predicted (3) Precisely to certain extent if codon […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Why Does a Mutant DNA Polymerase Show Higher Error Rate and Synthesize Short DNA Fragments?
49. A mutant DNA polymerase was found to have higher error rate and synthesized only short DNA fragments. In the statements below, potential explanations are given. A. The 5′ to […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
How Aminoacyl-tRNA Synthetases Recognize tRNAs: The Crucial Roles of Acceptor Stem and Anticodon Loop
9. The specificity of tRNA recognition by a aminoacyl tRNAsynthetase that is intrinsic to the tRNA molecule lies on (1) acceptor stem. (2) anticodon loop. (3) acceptor stem and anticodon […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Understanding E. coli DNA Polymerase I and III: Processivity, Exonuclease Activities, and Roles in Replication
The following statements refer to the E. coli replicative DNA polymerase: (A) DNA POI I displays very limited processivity and possesses 3’à5′ exonuclease activity, allowing fidelity of DNA replication. (B) […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
Aminoacylation of tRNA by Aminoacyl-tRNA Synthetase: The First Step in Translational Proofreading
Which of the following is the first step in translational proof reading? (1) Amino-acylation of t-RNA by amino acyl t-RNA synthetase (2) Peptide bond formation (3) Entry into A site […]
CSIR NET Life Science Previous Year Questions and Solution on DNA REPLICATION
Understanding the Role of DNA Polymerases in E. coli Chromosomal DNA Replication
for Escherichia coli chromosomal DNA replication, which one of the following statements is true? (1) DNA polymerase I is the main polymerase required for DNA replication (2) DNA polymerase I […]
CSIR NET Life Science Previous Year Questions and Solution on Molecular Biology
EF-Tu Escorts Aminoacyl-tRNAs to the Ribosome During Prokaryotic Translation Elongation
Aminoacyl tRNAs are escorted to the ribosome by the elongation factor (1) EF-Ts (2) EF-G (3) EF-Tu (4) Eef-2 Aminoacyl-tRNAs Are Escorted to the Ribosome by Elongation Factor EF-Tu During […]
