In an experiment, activin-secreting beads were placed on unspecified cells from an early Xenopus embryo. The activin then diffused from the beads. If the beads contained 1nM of activin, it […]
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CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Activin Morphogen Gradient in Xenopus: Differential Gene Activation and Cell Fate Determination
59. A “morphogen” can determine the fate of a cell by its concentration. Given below are some statements on the experiment performed to study the gradient- dependent effect of the […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Noggin in Xenopus Embryos: Rescuing Dorsal Structures and Neural Tube Formation after UV Treatment
In Xenopus, the Noggin protein, accomplishes two major functions of the organizer: it induces dorsal ectoderm to form neural tissues, and it dorsalizes mesoderm cells. Which one of the following […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Noggin mRNA Injection in Frog Embryos: Mimicking Organizer Function and Inducing Secondary Axis Formation
Injection of Noggin mRNA in cells that will become the future ventral side of a frog embryo mimics the effect of an organizer graft to the ventral side. This experiment […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Understanding Amphibian Early Embryonic Development: Nieuwkoop Center, Organizer Secretions, Neural Induction, and BMP Signaling
56. The following statements are made regarding the amphibian early-embryonic development: A. The Nieuwkoop center cells are mesodermal in origin. B. Chordin, Noggin and Goosecoid are secreted by the Organizer. […]
CSIR NET Life Science Previous Year Questions and Solution on Development Biology
Myxamoebae: Unlocking the Evolution of Multicellularity Through Aggregation and Fruiting Body Formation
The myxamoebae are in the vegetative stage where they feed on bacteria but enter the aggregation stage during nutrient starvation finally forming fruiting body with two types of differentiated cells. […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Roles of Fibronectin, BMP Inhibition, Wnt Signaling, and Nodal Proteins in Amphibian Development: Migration, Neural Induction, and Patterning
Following statements are made regarding amphibian development: A. Fibronectin plays an important role in enabling the mesodermal cells to migrate into the embryo. B. Organizer secrete proteins that block the […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Key Principles of Amphibian Development: The Nieuwkoop Centre, Organizer Function, BMP Signaling, and Wnt in Neural Patterning
Which one of the following statements with respect to amphibian development is correct? (1) The organizer is itself induced by the Nieuwkoop Centre located in the dorsal most mesodermal cells. […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Dominant Negative GSK3 in Xenopus Ventral Cells: Induction of Secondary Axis and Role in Dorsal-Ventral Axis Formation
52. In Xenopus embryos, β-catenin plays an important role in the Dorsal/Ventral axis development. What would you expect if the endogenous glycogen synthase kinase 3 (GSK3) is knocked out by […]
CSIR NET Life Science Previous Year Questions and Solution on Basic Concepts of Development
Dominant-Negative GSK3 Expression in Ventral Amphibian Embryos: Mechanism, Outcome, and Axis Duplication
51. The presence of β-catenin in the nuclei of blastomeres in the dorsal portion of the amphibian embryo is one of the determinants for laying down the dorso-ventral axis. What […]
