Q.43 The sequence of a 1 Mb long DNA is random. This DNA has all four basesoccurring in equal proportion. The number of nucleotides, on average, between twosuccessive EcoRI recognition […]
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![Q.42 Determine the correctness or otherwise of the following Assertion [a] and the Reason [r] Assertion [a]: A genetically engineered rice that produces beta-carotene in the rice grain is called Golden rice Reason [r]: Enabling biosynthesis of provitamin A in the rive endosperm gives a characteristic yellow orange color (A) Both [a] and [n] are false (B) Both [a] and [r] are true but is not the correct reason for [a] (C) Both [a] and are true and is the correct reason for [a] (D) [A] is true but [r] is false](https://www.letstalkacademy.com/wp-content/uploads/2026/01/slide_42-10.png)
GATE Biotechnology 2020 Previous Year Papers with Solutions
Golden Rice Beta-Carotene Production
Q.42 Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]Assertion [a]: A genetically engineered rice that produces beta–carotene in the rice grain is called Golden […]
![Q.41 Which of the following statements about gene therapy are CORRECT? [P] Affected individuals, but not their progeny, can be cured through germline gene theraphy [Q] Affected individuals, as well as their progeny, can be cured through germline gene therapy [R] Affected individuals, but not their progeny, can be cured through somatic gene theraphy [S] Affected individuals, as well as their progeny, can be cure through somatic gene therapy (A) P and R only (B) P and S only (C) Q and R only (D) Q and S only](https://www.letstalkacademy.com/wp-content/uploads/2026/01/slide_41-10.png)
GATE Biotechnology 2020 Previous Year Papers with Solutions
Gene Therapy Somatic vs Germline
Q.41 Which of the following statements about gene therapy are CORRECT?[P] Affected individuals, but not their progeny, can be cured through germline gene theraphy[Q] Affected individuals, as well as their […]
![Q.40 Determine the correctness or otherwise of the following Assertion [a] and the Reason [r] Assertion [a]: A typule and its immediate descendant cells are specialized and are called toipotent Reason [C]: Totipotent cells retain the capacity to differentiate into only a few cell types (A) Both [a] and [r] are false (B) Both [a] and [r] are true but [r] is not the correct reason for [a] (C) Both [a] and [r] are true and [r] is the correct reason for [a] (D) [a] is true but is false](https://www.letstalkacademy.com/wp-content/uploads/2026/01/slide_40-10.png)
GATE Biotechnology 2020 Previous Year Papers with Solutions
Totipotent Cells Assertion Reason
Q.40 Determine the correctness or otherwise of the following Assertion [a] and the Reason [r] Assertion [a]: A typule and its immediate descendant cells are specialized and are called toipotent […]
![Q.39 Which of the following strategies are used by cells for metabolic regulation! [P] Phosphorylation- dephosphorylation [Q] Allostery [R| Feedback inhibition (A) P and Q only (B) P and R only (C) Q and R only (D) P, Q and R](https://www.letstalkacademy.com/wp-content/uploads/2026/01/slide_39-10.png)
GATE Biotechnology 2020 Previous Year Papers with Solutions
Cells Metabolic Regulation Strategies
Q.39 Which of the following strategies are used by cells for metabolic regulation! [P] Phosphorylation- dephosphorylation [Q] Allostery [R| Feedback inhibition (A) P and Q only (B) P and R […]
![Q.No. 38 Match sub-cellular organelles listed in Group I with their features listed in Group II: Group I Group II P] Mitochondrion 1. Single-membrane enclosed Q] Chloroplast 2. Double-membrane enclosed R] Nucleus 3. Maternal inheritance S] Endoplasmic reticulum 4. Endosymbiotic origin Options: P-1, Q-4, R-2, S-3 P-2, Q-3, R-4, S-1 P-3, Q-4, R-2, S-1 P-3, Q-1, R-4, S-2](https://www.letstalkacademy.com/wp-content/uploads/2026/01/slide_38-10.png)
GATE Biotechnology 2020 Previous Year Papers with Solutions
Match Sub-cellular Organelles with Their Features
Q.No. 38 Match sub-cellular organelles listed in Group I with their features listed in Group II: Group I Group II P] Mitochondrion 1. Single-membrane enclosed Q] Chloroplast 2. Double-membrane enclosed […]
![Q.37 The schematic of a plasmid with a gap in one of the strands is shown below: Which of the following enzyme(s) is/are required to fill the gap and generate a covalently closed circular plasmid? [P] DNA ligase [Q] Alkaline phosphatase [R] DNA polymerase [S] Polynucletoide Kinase](https://www.letstalkacademy.com/wp-content/uploads/2026/01/slide_37-10.png)
GATE Biotechnology 2020 Previous Year Papers with Solutions
Enzymes Required to Fill Plasmid Gap
Q.37 The schematic of a plasmid with a gap in one of the strands is shown below:Which of the following enzyme(s) is/are required to fill the gap and generate acovalently […]
![Q.36 Determine the correctness or otherwise of the following Assertion (a) and the Reasonv[r]. Assertion [a]: Embryonic stem cells are suitable for developing knockout mice Reason [r]: Homologous recombination is more frequent in embryonic stem cells than that in somatic cells (A) Both [a] and [r] are false (B) Both [a] and [r] are true, and [r] is the correct reason for [a] (C) Both [a] and [r] are true, but [r] is not the correct reason for [a] (D) [a] is true, but [r] is false](https://www.letstalkacademy.com/wp-content/uploads/2026/01/slide_36-10.png)
GATE Biotechnology 2020 Previous Year Papers with Solutions
Embryonic Stem Cells for Knockout Mice
Q.36 Determine the correctness or otherwise of the following Assertion (a) and the Reasonv[r].Assertion [a]: Embryonic stem cells are suitable for developing knockout miceReason [r]: Homologous recombination is more frequent […]
![Q.35 Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]. Assertion [a]: Dam methylase protects E. coli DNA from phage endonucleases Reason [r]: E. coli Dam methylase methylates the adenosine residue in the sequence "GATC" (A) Both [a] and [r] are true and [r) is the correct reason for [a] (B) Both [a] and [r) are true but [r] is not the correct reason for [a] (C) Both [a] and [r] are false (D) [a] is false but [r] is true](https://www.letstalkacademy.com/wp-content/uploads/2026/01/slide_35-10.png)
GATE Biotechnology 2020 Previous Year Papers with Solutions
Dam Methylase E. coli Protection
Q.35 Determine the correctness or otherwise of the following Assertion [a] and the Reason [r].Assertion [a]: Dam methylase protects E. coli DNA from phage endonucleasesReason [r]: E. coli Dam methylase […]
![Q.No. 34 A list of pathogens (Group I) and a list of anti-microbial agents (Group II) used to treat their infections are given below. Match the pathogens with the corresponding anti-microbial agents. Group I Group II P] Influenza A virus 1. Isoniazid Q] Fungus 2. Amantadine R] Plasmodium 3. Fluconazole S] Mycobacterium 4. Artemisinin 5. Iodoquinol Options: P-4, Q-3, R-2, S-5 P-5, Q-2, R-4, S-1 P-2, Q-3, R-4, S-1 P-2, Q-3, R-1, S-5](https://www.letstalkacademy.com/wp-content/uploads/2026/01/slide_34-10.png)
GATE Biotechnology 2020 Previous Year Papers with Solutions
Match Pathogens with Anti-Microbial Agents
Q.No. 34 A list of pathogens (Group I) and a list of anti-microbial agents (Group II) used to treat their infections are given below. Match the pathogens with the corresponding […]
