Q.No. 34
A list of pathogens (Group I) and a list of anti-microbial agents (Group II) used to treat their infections are given below.
Match the pathogens with the corresponding anti-microbial agents.
| Group I | Group II |
|---|---|
| P] Influenza A virus | 1. Isoniazid |
| Q] Fungus | 2. Amantadine |
| R] Plasmodium | 3. Fluconazole |
| S] Mycobacterium | 4. Artemisinin |
| 5. Iodoquinol |
Options:
- P-4, Q-3, R-2, S-5
- P-5, Q-2, R-4, S-1
- P-2, Q-3, R-4, S-1
- P-2, Q-3, R-1, S-5
Correct Match
| Group I (Pathogens) | Group II (Drugs) |
|---|---|
| P – Influenza A virus | 2 – Amantadine |
| Q – Fungus | 3 – Fluconazole |
| R – Plasmodium | 4 – Artemisinin |
| S – Mycobacterium | 1 – Isoniazid |
Correct Option: P-2, Q-3, R-4, S-1
Introduction
Medical entrance and competitive exams frequently ask students to match pathogens with the drug that effectively treats them.
Correct identification ensures proper treatment and saves lives. Below is a complete breakdown of four major pathogens and
the corresponding antimicrobial agents used against them.
Pathogens and Their Correct Drugs
P. Influenza A Virus → Amantadine (2)
Amantadine is an antiviral medicine used to treat Influenza A virus infections. It works by blocking the M2 proton channel,
preventing viral uncoating and replication. It has no effect against Influenza B or fungal, bacterial, or parasitic infections.
Q. Fungus → Fluconazole (3)
Fluconazole is a well-known antifungal agent. It acts by inhibiting ergosterol synthesis, which weakens the fungal cell membrane.
It is commonly used to treat candidiasis and cryptococcal infections, and is ineffective for bacteria, viruses or parasites.
R. Plasmodium → Artemisinin (4)
Artemisinin is one of the most effective treatments for Plasmodium falciparum malaria. It kills parasites by releasing
free radicals within infected red blood cells. It does not act on viruses, bacteria or fungi.
S. Mycobacterium → Isoniazid (1)
Isoniazid (INH) is a first-line anti-tuberculosis drug used to treat Mycobacterium infections. It works by blocking
mycolic acid synthesis, preventing cell wall formation. It is ineffective against viruses, fungi, or malaria parasites.
Final Matching Summary
| Pathogen | Correct Drug |
|---|---|
| Influenza A virus | Amantadine |
| Fungus | Fluconazole |
| Plasmodium | Artemisinin |
| Mycobacterium | Isoniazid |
Correct Answer: P-2, Q-3, R-4, S-1
Conclusion
Each antimicrobial agent targets a specific organism type. Understanding these drug-pathogen relationships builds
a strong foundation in microbiology and clinical medicine.


