AsO43- is chemically very similar to PO43- and could be used as an alternate substrate by phosphate requiring enzymes. When 1,3-bisphospho-glycerate is converted to 3-phosphoglycerate, A TP is generated. However, […]
Blog
Understanding ATP Production in Glycolysis and the Citric Acid Cycle: Key Facts and Clarifications
The glycolysis and citric acid cycles are important pathways o generate energy in the cell. Given below are statements regarding the production of ATP. A. Electrons released during the oxidative […]
How Glucose-6-Phosphate Dehydrogenase Deficiency Confers Resistance to Malaria
A person suffering from glucose-6-phosphate dehydrogenase deficiency are found to be resistant to (1) Plasmodium (2) Fungus (3) Leishmania (4) Bacteria Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most […]
Impact of Oxygen Supply on Cancer Cell Metabolism and Tumor Microenvironment: Understanding HIF-1α, Warburg Effect, and Lactate Production
The gradient of oxygen available to cells at inner regions of a tumour tissue environment is typically low that creates a hypoxic micro-environment. If enough oxygen is supplied to the […]
Common Misconceptions About Glycolysis: Identifying Incorrect Statements on Pyruvate Kinase and Anaerobic Function
The following are some statements regarding glycolysis: A. Glycolysis is not regulated by pyruvate kinase. B. Lactate can be an end product of glycolysis. C. Glycolysis cannot function anaerobically. D. […]
NAD+ Recycling in Submerged Mangrove Roots: The Role of Fermentative Glycolysis
In submerged roots of mangrove plants, the recycling of NAD+ produced during glucose oxidation, is carried out by (1) Gluconeogenesis (2) Glyoxylate cycle (3) Electron transport chain (4) Fermentative glycolysis […]
Alanine and Amino Acid Biosynthesis in Plants: The Role of Pyruvate as a Key Precursor
During glycolysis in plants, alanine and related amino acids are directly produced from which one of the following precursors? (1) 3-Phosphoglycerate (2) Phosphoenolpyruvate (3) Pyruvate (4) Acetyl-CoA Amino acid biosynthesis […]
Physiological Significance of Liver Alcohol Dehydrogenase (L-ADH) in Mammals Beyond Fermentation
In yeast, under anaerobic conditions, pyruvate is fermented to ethanol through two steps: decarboxylation of pyruvate to acetaldehyde and NADH-mediated reduction of acetaldehyde to ethanol. The mammalian liver also expresses […]
How Yeast Converts Acetaldehyde to Ethanol: The Role of NAD+ Regeneration in Fermentation
When yeast produce ethanol from glucose, the reaction of acetaldehyde to form ethanol directly (1) generates ATP (2) produces NADH (3) regenerates NAD+ (4) contributes to the proton motive force […]
The End Product of Glycolysis in Mature Erythrocytes: Understanding Lactate Formation
In mature erythrocytes, the end-product of glycolysis that contains the carbons of glucose is: (1) ethanol (2) pyruvate (3) acetaldehyde (4) lactate Mature erythrocytes (red blood cells) have a unique […]


