3. Which of the following is the last to occur after the binding of a sea urchin sperm to an egg? (1) Initiation of mRNA synthesis (2) Increase in cytosolic […]
Blog
Mosaic Developmental Pattern Explained: Autonomous or Conditional?
Mosaic developmental pattern is always (1) Autonomous (2) Non autonomous (3) Conditional (4) Regulative Mosaic developmental pattern is a fundamental concept in embryology describing how cells in an embryo acquire […]
Understanding the Role of Homeotic Genes in Development and Organ Formation
Homeotic genes are responsible for (1) Maintaining gaps in segments (2) Provide gradient for anterior posterior axis of embryo (3) Codes secretory morphogens (4) Formation of organ at defined locations […]
Why Morphologically Normal Sperms Fail to Exhibit Hyperactivation: The Role of Capacitation
Sperms are morphologically fit but are unable to actively swim (hyper activation) due to lack of (1) Spermatogenesis (2) Spermiogenesis (3) Prostrate glands (4) Capacitation Introduction to Sperm Motility and […]
Homeotic Genes: Master Regulators of Developmental Anatomy
Homeotic genes are responsible for (1) Development of anatomical structures (2) Homeostasis (3) Cell cycle regulation (4) Adaptation to stress Homeotic genes are fundamental genetic components that orchestrate the blueprint […]
Understanding Androgenetic Embryos: Experiment, Mechanism, and Developmental Outcomes
From a newly fertilized mouse egg, maternal pronucleus was removed and replaced with a second paternal pronucleus. Following observations/ statements were made: (A) This will result in formation of an […]
VE-Cadherin’s Role in Endothelial Cell Survival Through VEGF Signaling: Why N-cadherin Compensation Fails
52. Vascular endothelial (VE)-cadherin is an important cell adhesion molecule for endothelial cells. Endothelial cells that are unable to express VE-cadherin still can adhere to one another via N-cadherin (neural […]
Role of N-Cadherin in Mesenchymal Condensation and Limb Skeletal Development in Mammalian Embryos
51. Temporal expression of N-cadherin is extremely important during early development of the mammalian embryos. Accordingly, which one of the following statements about N-cadherin is true? (1) Injection of N-cadherin […]
Impact of N-Cadherin and N-CAM Mutations on Embryonic Development and Nervous System Formation
Cadherins mediate Ca2+-dependent cell-cell adhesion and play an important role in embryonic development by changing the adhesive properties of cell. Aggregation of nerve cells to form an epithelium is correlated […]
Cyclopamine Inhibition of Hedgehog Pathway: Blocking Ci/Gli Transcription Activation in Cells
Preventing the blocking action of Patched protein leads to activation of Cos-2, which dissociates itself from microtubules, activates Ci/Gli which binds to CBP (CREB- binding protein) and promotes transcription of […]


