Q.21 Intracellular proteins are targeted for proteolytic degradation in proteasomes uponconjugation with(A) ubiquitin(B) integrin(C) peptidase(D) calreticulin Answer: (A) ubiquitin Intracellular proteins undergo proteolytic degradation in proteasomes after conjugation with ubiquitin, […]
Tag: GATE Biotechnology Previous Year Papers with Solutions
Tag: GATE Biotechnology Previous Year Papers with Solutions
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Bacteriophage Infection Sequence
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- January 10, 2026
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Q.20 The correct sequence of events during bacteriophage infection of a bacterial cell is(A) landing → attachment → tail contraction → penetration and unplugging → DNAejection(B) attachment → landing → […]
Leghemoglobin Function
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- January 10, 2026
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Q.19 Which one of the following statements is TRUE about leghemoglobin?(A) It binds oxygen to protect nitrogenase(B) It binds hemoglobin to protect oxygenase(C) It binds oxygen to protect hydrogenase(D) It […]
B-Cell Development in Bone Marrow
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- January 10, 2026
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Q.18 Which one of the following is required for the development of B–cells in the bonemarrow?(A) Stromal cells(B) Dendritic cells(C) Kupffer cells(D) NK cells Stromal cells are required for B-cell […]
BATF3 in Dendritic Cell Cross-Presentation
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- January 10, 2026
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Q.17 Dendritic cells are involved in cross–presentation of antigens. Which of thefollowing protein(s) is(are) required for cross–presentation?P. Basic leucine zipper ATF–like transcription factor 3 (BATF3)Q. Membrane associated ring–CH–type finger 1 […]
Which Drug is NOT an Immune Checkpoint Inhibitor?
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- January 10, 2026
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Q.16 Which one of the following drugs is NOT an immune checkpoint inhibitor?(A) Ipilimumab(B) Pembrolizumab(C) Nivolumab(D) Trastuzumab Trastuzumab is not an immune checkpoint inhibitor. Ipilimumab, Pembrolizumab, and Nivolumab target immune checkpoints […]
C-Value Paradox Explained
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- January 10, 2026
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Q.15 C–value paradox refers to(A) the lack of correlation between genome size and genetic complexity of anorganism(B) the presence of genetic sequences that propagate themselves within a genome(C) the coexistence […]
Chromosome Mutations Assertion-Reason
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- January 10, 2026
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Q.14 Determine the correctness or otherwise of the following Assertion [a] and theReason [r].Assertion [a]: Chromosome mutations can change the structure of chromosomes.Reason [r]: All chromosome mutations arise due to […]
Multicellular Organisms Gene Expression Profiles
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- January 10, 2026
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Q.13 Determine the correctness or otherwise of the following Assertion [a] and theReason [r].Assertion [a]: In multicellular organisms, cells of different lineages have differentgene expression profiles.Reason [r]: Alternative splicing is […]
Acetylcholine Parasympathetic Nerves Heart Pacemaker Cells
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- January 10, 2026
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Q.12 Acetylcholine released by the parasympathetic nerves has which one of thefollowing functions in the heart pacemaker cells?(A) It binds to GPCR and activates G protein to slow the heart […]


